Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 12/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL419690 | 0.86 | ERN1 (0.58) | ERN1SMN1; SMN2KDM4EMEN1USP2 | |
| SCHEMBL2477063 | 0.81 | ERN1 (0.52) | ERN1SMN1; SMN2KDM4EMEN1USP2 | |
| SCHEMBL28311710 | 0.81 | ERN1 (0.47) | ERN1SMN1; SMN2KDM4EMEN1USP2 | |
| SCHEMBL29785434 | 0.81 | ERN1 (0.47) | ERN1SMN1; SMN2KDM4EMEN1USP2 | |
| SCHEMBL12813802 | 0.81 | ERN1 (0.47) | ERN1SMN1; SMN2KDM4EMEN1USP2 | |
| SCHEMBL18574482 | 0.80 | GABRA1 (0.52) | SMN1; SMN2KDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL187267 | 0.79 | ALOX5 (0.49) | ERN1SMN1; SMN2KDM4EMEN1USP2 | |
| SCHEMBL29467329 | 0.79 | ALOX5 (0.49) | ERN1SMN1; SMN2KDM4EMEN1USP2 | |
| SCHEMBL29467330 | 0.79 | ALOX5 (0.49) | ERN1SMN1; SMN2KDM4EMEN1USP2 | |
| SCHEMBL31532241 | 0.78 | ALOX5 (0.48) | ERN1SMN1; SMN2KDM4EMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040454-A2 | SYNTHESIS OF SUBSTITUTED SALICYLALDEHYDE DERIVATIVES | NOVOMER, INC. (US) | 2012-03-29 | — | — | WO | disclosed |