Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 6/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.31 |
| ▸ | ACACB | O00763 | 3/20 | 0.31 |
| ▸ | ACACA | Q13085 | 3/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15107417 | 0.89 | PGR (0.35) | CYP11B2PGRACACBACACA | |
| SCHEMBL10079523 | 0.87 | HDAC2 (0.39) | HDAC2HDAC1CYP11B2ACACBACACA | |
| SCHEMBL10079442 | 0.80 | ACACB (0.45) | CYP11B2ACACBACACA | |
| SCHEMBL10079443 | 0.78 | CYP11B2 (0.38) | HDAC2HDAC1CYP11B2PGRACACB | |
| SCHEMBL15107412 | 0.77 | ACACB (0.38) | CYP11B2ACACBACACA | |
| SCHEMBL10079505 | 0.77 | CYP11B2 (0.36) | CYP11B2PGROPRL1GRIN2B | |
| SCHEMBL6113540 | 0.76 | ACACB (0.52) | HDAC2HDAC1MMP1MMP13ACACB | |
| SCHEMBL13263793 | 0.74 | HDAC2 (0.32) | HDAC2HDAC1 | |
| SCHEMBL10079525 | 0.74 | HDAC2 (0.34) | HDAC2HDAC1CYP11B2 | |
| SCHEMBL10079512 | 0.72 | CYP11B2 (0.39) | CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8487118-B2 | Cyclic diones and their use as insecticides, acaricides and/or fungicides | BAYER CROPSCIENCE AG (DE) | 2013-07-16 | — | — | US | disclosed |
| US-8487118-B2 | Cyclic diones and their use as insecticides, acaricides and/or fungicides | BAYER CROPSCIENCE AG (DE) | 2013-07-16 | — | — | US | disclosed |
| US-20120046464-A1 | Cyclic Diones and Their Use as Insecticides, Acaricides and/or Fungicides | BAYER CROPSCIENCE AG (DE) | 2012-02-23 | — | — | US | disclosed |
| US-20120046464-A1 | Cyclic Diones and Their Use as Insecticides, Acaricides and/or Fungicides | BAYER CROPSCIENCE AG (DE) | 2012-02-23 | — | — | US | disclosed |
| WO-2010081689-A2 | CYCLIC DIONES AND THEIR USE AS INSECTICIDES, ACARICIDES AND/OR FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2010-07-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046464-A1 | Cyclic Diones and Their Use as Insecticides, Acaricides and/or Fungicides | DDT, CYP19A1, RDX | HDAC2 800/4885HDAC1 462/4885CYP11B2 465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.