SCHEMBL10079658

SCHEMBL10079658

C=Cc1cccc(C(C)(C)c2cccc(C)n2)n1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
KDM4E B2RXH2 2/20 0.39
HPGD P15428 2/20 0.39
NPC1 O15118 1/20 0.39
GRM5 P41594 1/20 0.39
RAB9A P51151 1/20 0.39
GRM4 Q14833 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
MEN1 O00255 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
PKM P14618 1/20 0.39
TSHR P16473 1/20 0.39
NFKB1 P19838 1/20 0.39
CYP2C19 P33261 1/20 0.39
THPO P40225 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13821747 0.83 CCR1 (0.50) ALDH1A1KDM4EHPGDNPC1GRM5
SCHEMBL93618 0.81
SCHEMBL9004164 0.80 CCR4 (0.32)
Bromide SCHEMBL31442913 0.79 ALDH1A1 (0.52) ALDH1A1KDM4EHPGDNPC1GRM5
SCHEMBL14721820 0.74 CCR1 (0.64) ALDH1A1KDM4EHPGDNPC1GRM5
SCHEMBL31442917 0.74 MEN1 (0.47) ALDH1A1KDM4EHPGDNPC1GRM5
SCHEMBL19801082 0.74
SCHEMBL12510668 0.74
SCHEMBL24897237 0.73 CCR1 (0.40) ALDH1A1KDM4EHPGDNPC1GRM5
SCHEMBL931543 0.72 P2RX7 (0.40) GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2036907-B1 Organic electroluminescence device FUJIFILM CORP (JP) 2012-02-29 EP disclosed