Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14724450 | 0.86 | EGLN1 (0.36) | PIM1 | |
| SCHEMBL2501457 | 0.83 | EGLN1 (0.52) | — | |
| SCHEMBL10079304 | 0.71 | ERCC5 (0.44) | — | |
| SCHEMBL10080435 | 0.64 | EGLN1 (0.62) | — | |
| SCHEMBL2502552 | 0.59 | EGLN1 (0.53) | — | |
| SCHEMBL31248722 | 0.58 | SCN9A (0.35) | — | |
| SCHEMBL21152517 | 0.58 | PIM1 (0.34) | PIM1 | |
| SCHEMBL2500250 | 0.58 | EGLN1 (0.62) | — | |
| SCHEMBL35212365 | 0.58 | ALDH1A1 (0.74) | — | |
| SCHEMBL10962357 | 0.58 | ALDH1A1 (0.74) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2150251-B1 | THIENOPYRIDINE AND THIAZOLOPYRIDINE DERIVATIVES THAT INHIBIT PROLYL HYDROXYLASE ACTIVITY | AMGEN INC (US) | 2012-06-27 | — | — | EP | disclosed |