Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | GUSB | P08236 | 3/20 | 0.37 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 3/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.35 |
| ▸ | NUAK2 | Q9H093 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12156234 | 0.90 | SMN1; SMN2 (0.40) | SMN1; SMN2BRD4GUSBHTR2CHTR1A | |
| SCHEMBL1706072 | 0.88 | HTR6 (0.46) | RAD52SMN1; SMN2BRD4GUSBHTR2C | |
| SCHEMBL1706085 | 0.77 | SMN1; SMN2 (0.40) | SMN1; SMN2BRD4GUSBHTR2CHTR1A | |
| SCHEMBL1705567 | 0.77 | SMN1; SMN2 (0.40) | SMN1; SMN2BRD4GUSBHTR2CHTR1A | |
| SCHEMBL1705603 | 0.77 | SMN1; SMN2 (0.40) | SMN1; SMN2BRD4GUSBHTR2CHTR1A | |
| SCHEMBL12156232 | 0.76 | HTR6 (0.43) | RAD52SMN1; SMN2BRD4GUSBHTR2C | |
| SCHEMBL1705585 | 0.74 | ADRA2C (0.41) | HTR6MAPTMEN1KMT2AEGFR | |
| SCHEMBL1706545 | 0.74 | HRH4 (0.41) | HTR6MAPTMEN1KMT2AEGFR | |
| SCHEMBL12161117 | 0.74 | S1PR1 (0.56) | RAD52SMN1; SMN2BRD4GUSBHTR2C | |
| SCHEMBL12156278 | 0.73 | SMN1; SMN2 (0.39) | SMN1; SMN2BRD4GUSBHTR2CHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2177512-B1 | INHIBITOR OF BINDING OF S1P1 | TAISHO PHARMACEUTICAL CO LTD (JP) | 2012-04-18 | — | — | EP | disclosed |