SCHEMBL10080348

SCHEMBL10080348

C=CC(=O)OCCCCOC(=O)CCC(=O)OC

nearest known ligand 0.62

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.62
ALDH1A1 P00352 4/20 0.62
CYP3A4 P08684 1/20 0.62
HPGD P15428 1/20 0.56
TP53 P04637 2/20 0.47
HIF1A Q16665 2/20 0.47
HSD17B10 Q99714 1/20 0.47
LMNA P02545 1/20 0.44
THRB P10828 2/20 0.40
HTR2C P28335 1/20 0.40
ADRA2A P08913 1/20 0.38
ADRA1A P35348 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
MAPT P10636 1/20 0.37
BLM P54132 1/20 0.37
ATM Q13315 1/20 0.37
NAAA Q02083 1/20 0.36
DGKA P23743 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28181728 0.96 TSHR (0.57) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL12744514 0.93 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL2611999 0.93 TSHR (0.55) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL2612362 0.91 TSHR (0.64) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL26093280 0.91 TSHR (0.75) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL12270648 0.89 TSHR (0.68) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL12270651 0.89 TSHR (0.68) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL2612363 0.89 TSHR (0.68) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL5935034 0.89 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL17696341 0.88 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118201968-A Photocurable composition 三键有限公司 2024-06-14 CN disclosed
CN-118175988-A Photocurable composition for nail or artificial nail 三键有限公司 2024-06-11 CN disclosed
CN-118146724-A Curable resin composition, cured product, laminate comprising cured product, and method for disassembling laminate 三键有限公司 2024-06-07 CN disclosed
CN-118103412-A Photocurable composition 三键有限公司 2024-05-28 CN disclosed
CN-116744900-A Photocurable resin composition for nail or artificial nail, cured product thereof, and method for covering nail or artificial nail 三键有限公司 2023-09-12 CN disclosed
US-20230212136-A1 CURABLE RESIN COMPOSITION, CURED PRODUCT, DIFFRACTIVE OPTICAL ELEMENT, AND MULTILAYER DIFFRACTIVE OPTICAL ELEMENT FUJIFILM CORPORATION (JP) 2023-07-06 US disclosed
US-20230212136-A1 CURABLE RESIN COMPOSITION, CURED PRODUCT, DIFFRACTIVE OPTICAL ELEMENT, AND MULTILAYER DIFFRACTIVE OPTICAL ELEMENT FUJIFILM CORPORATION (JP) 2023-07-06 US disclosed
US-20170349828-A1 POLYMERIZABLE COMPOSITION, FILM, AND HALF MIRROR FOR DISPLAYING PROJECTION IMAGE FUJIFILM CORPORATION (JP) 2017-12-07 US disclosed
US-20160108315-A1 OPTICALLY ANISOTROPIC LAYER, METHOD FOR PRODUCING THE OPTICALLY ANISOTROPIC LAYER, A LAMINATE, POLARIZING PLATE, DISPLAY DEVICE, LIQUID CRYSTAL COMPOUND, METHOD FOR PRODUCING THE LIQUID CRYSTAL COMPOUND, AND CARBOXYLIC ACID COMPOUND FUJIFILM CORPORATION (JP) 2016-04-21 US disclosed
US-8454857-B2 Polymerizable liquid crystal compounds, polymerizable liquid crystal compositions, liquid crystalline polymers and optically anisotropic materials ZEON CORPORATION (JP) 2013-06-04 US disclosed
US-8262931-B2 Polymerizable liquid crystal compound, polymerizable liquid crystal composition, polymer and film FUJIFILM CORPORATION (JP) 2012-09-11 US disclosed
US-8158021-B2 Polymerizable liquid crystal compound, polymerizable liquid crystal composition, liquid crystalline polymer, and optical anisotropic article ZEON CORPORATION (JP) 2012-04-17 US disclosed
US-20110233464-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, POLYMER AND FILM FUJIFILM CORPORATION (JP) 2011-09-29 US disclosed
US-20110237768-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, POLYMER AND FILM FUJIFILM CORPORATION (JP) 2011-09-29 US disclosed
US-20100258764-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTALLINE POLYMER, AND OPTICAL ANISOTROPIC ARTICLE ZEON CORPORATION (JP) 2010-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100258764-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTALLINE POLYMER, AND OPTICAL ANISOTROPIC ARTICLE LEO1, ZYX, CCNT1 TSHR 4760/4885ALDH1A1 2720/4885CYP3A4 2218/4885
US-20230212136-A1 CURABLE RESIN COMPOSITION, CURED PRODUCT, DIFFRACTIVE OPTICAL ELEMENT, AND MULTILAYER DIFFRACTIVE OPTICAL ELEMENT TERB1, RER1, LARP1 TSHR 3138/4885ALDH1A1 228/4885CYP3A4 2849/4885
US-20110237768-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, POLYMER AND FILM SCO2, NR0B2, NR0B1 TSHR 2025/4885ALDH1A1 4245/4885CYP3A4 2502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.