Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.53 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6345911 | 0.88 | GRIN2D (0.59) | GRIN2DGRIN2AGRIN2CALDH1A1CYP1A2 | |
| SCHEMBL10081747 | 0.88 | GRIN2D (0.68) | GRIN2DGRIN2AGRIN2CALDH1A1CYP1A2 | |
| SCHEMBL28170198 | 0.81 | PTPN1 (0.59) | GRIN2DGRIN2AGRIN2CALDH1A1CYP2C9 | |
| SCHEMBL15439625 | 0.80 | GRIN2D (0.67) | GRIN2DGRIN2AGRIN2CALDH1A1CYP1A2 | |
| SCHEMBL10484184 | 0.80 | GRIN2D (0.67) | GRIN2DGRIN2AGRIN2CALDH1A1CYP1A2 | |
| SCHEMBL10484311 | 0.80 | ALDH1A1 (0.68) | GRIN2DGRIN2AGRIN2CALDH1A1CYP1A2 | |
| SCHEMBL31742339 | 0.80 | GRIN2D (0.67) | GRIN2DGRIN2AGRIN2CALDH1A1CYP1A2 | |
| SCHEMBL30771554 | 0.80 | HIPK2 (0.57) | PARP1CSNK2A1HIPK2 | |
| SCHEMBL20718400 | 0.80 | HIPK2 (0.57) | PARP1CSNK2A1HIPK2 | |
| SCHEMBL28432123 | 0.79 | HIPK2 (0.56) | PARP1CSNK2A1HIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012019106-A2 | POSITIVE AND NEGATIVE MODULATORS OF NMDA RECEPTORS | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2012-02-09 | — | — | WO | disclosed |