Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.57 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.57 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.57 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.57 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | PPM1D | O15297 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.39 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2197741 | 0.82 | PPM1D (0.53) | PPM1D | |
| SCHEMBL27712207 | 0.78 | MCL1 (0.41) | SPHK1KMT2APPM1DLNPEP | |
| SCHEMBL10080509 | 0.76 | GRIN2D (0.66) | GRIN2DGRIN2AGRIN2BGRIN2CDHODH | |
| SCHEMBL11071411 | 0.76 | GRIN2D (0.70) | GRIN2DGRIN2AGRIN2BGRIN2CKMT2A | |
| SCHEMBL10081274 | 0.75 | GRIN2D (0.68) | GRIN2DGRIN2AGRIN2BGRIN2CKMT2A | |
| SCHEMBL18917571 | 0.75 | GRIN2D (0.64) | GRIN2DGRIN2AGRIN2BGRIN2CDHODH | |
| SCHEMBL7331987 | 0.74 | GRIN2D (0.67) | GRIN2DGRIN2AGRIN2BGRIN2CKMT2A | |
| SCHEMBL7342564 | 0.74 | GRIN2D (0.67) | GRIN2DGRIN2AGRIN2BGRIN2CKMT2A | |
| SCHEMBL2403600 | 0.74 | GRIN2D (0.67) | GRIN2DGRIN2AGRIN2BGRIN2CKMT2A | |
| SCHEMBL8303752 | 0.74 | GRIN2D (0.67) | GRIN2DGRIN2AGRIN2BGRIN2CKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012019106-A2 | POSITIVE AND NEGATIVE MODULATORS OF NMDA RECEPTORS | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2012-02-09 | — | — | WO | disclosed |