SCHEMBL8303752

SCHEMBL8303752

CCCCCCCCc1ccc2cc(C(=O)O)ccc2c1

nearest known ligand 0.97

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.67
GRIN2A Q12879 1/20 0.67
GRIN2B Q13224 1/20 0.67
GRIN2C Q14957 1/20 0.67
RARB P10826 8/20 0.65
MEN1 O00255 1/20 0.65
ALDH1A1 P00352 1/20 0.65
RARA P10276 1/20 0.65
MAPT P10636 1/20 0.65
MTOR P42345 1/20 0.65
KMT2A Q03164 1/20 0.65
KAT8 Q9H7Z6 2/20 0.57
PPARA Q07869 1/20 0.57
TP53 P04637 1/20 0.54
TSHR P16473 1/20 0.54
PLA2G4A P47712 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7342564 1.00 GRIN2D (0.67) GRIN2DGRIN2AGRIN2BGRIN2CRARB
SCHEMBL7331987 1.00 GRIN2D (0.67) GRIN2DGRIN2AGRIN2BGRIN2CRARB
SCHEMBL2403600 1.00 GRIN2D (0.67) GRIN2DGRIN2AGRIN2BGRIN2CRARB
Hydrochloric Acid SCHEMBL10716592 0.98 GRIN2D (0.65) GRIN2DGRIN2AGRIN2BGRIN2CRARB
SCHEMBL10081274 0.98 GRIN2D (0.68) GRIN2DGRIN2AGRIN2BGRIN2CRARB
SCHEMBL11071411 0.94 GRIN2D (0.70) GRIN2DGRIN2AGRIN2BGRIN2CRARB
SCHEMBL17592174 0.87 GRIN2D (0.65) GRIN2DGRIN2AGRIN2BGRIN2CRARB
SCHEMBL10600377 0.86 THRA (0.55) GRIN2DGRIN2AGRIN2BGRIN2CRARB
SCHEMBL8152604 0.86 THRA (0.55) GRIN2DGRIN2AGRIN2BGRIN2CRARB
SCHEMBL18917571 0.86 GRIN2D (0.64) GRIN2DGRIN2AGRIN2BGRIN2CRARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0462578-B1 Mesomorphic compound for use in liquid crystal composition and liquid crystal device and display apparatus using same CANON KK (JP) 1999-09-22 EP disclosed
US-5244596-A Benzoxazoles CANON KABUSHIKI KAISHA (JP) 1993-09-14 US disclosed
EP-0462578-A1 Mesomorphic compound for use in liquid crystal composition and liquid crystal device and display apparatus using same CANON KABUSHIKI KAISHA (JP) 1991-12-27 EP disclosed