SCHEMBL10080677

SCHEMBL10080677

CC(C)C(NC(=O)C(CCCCNC(=O)OCc1ccccc1)NC(=O)OCc1ccccc1)C(=O)N1CCCC1C(=O)NC(C(=O)C(F)(F)F)C(C)C

nearest known ligand 0.60

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MALT1 Q9UDY8 1/20 0.60
CMA1 P23946 7/20 0.55
ELANE P08246 12/20 0.54
CTSG P08311 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7320588 0.89 MALT1 (0.59) MALT1
SCHEMBL7324440 0.89 MALT1 (0.59) MALT1CMA1ELANE
SCHEMBL10081595 0.87 ELANE (0.65) CMA1ELANECTSG
SCHEMBL7317534 0.86 ITGB3 (0.55) MALT1CMA1
SCHEMBL7355181 0.86 MALT1 (0.59) MALT1CMA1ELANE
SCHEMBL7311270 0.85 MALT1 (0.53) MALT1CMA1
SCHEMBL7314754 0.85 MALT1 (0.53) MALT1CMA1ELANE
SCHEMBL7320222 0.85 CMA1 (0.56) MALT1CMA1ELANE
SCHEMBL7321341 0.85 CMA1 (0.56) MALT1CMA1ELANE
SCHEMBL7309936 0.85 ITGB3 (0.59) MALT1CMA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9289388-B2 Methods and compositions for delivery of medicaments to the lungs PAKA PULMONARY PHARMACEUTICALS, INC. (US) 2016-03-22 US disclosed
US-20120010145-A1 Methods and Compositions for Delivery of Medicaments to the Lungs PAKA PULMONARY PHARMACEUTICALS, INC. 2012-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120010145-A1 Methods and Compositions for Delivery of Medicaments to the Lungs SMPD1, SMPD3, SGMS1 MALT1 4765/4885CMA1 409/4885ELANE 28/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.