Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | PLEC | Q15149 | 1/20 | 0.38 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | LPL | P06858 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12192021 | 0.85 | MEN1 (0.74) | MEN1KMT2ABLMTHRBRECQL | |
| SCHEMBL16081224 | 0.73 | MEN1 (0.57) | MEN1KMT2ABLMTHRBRECQL | |
| SCHEMBL10082262 | 0.73 | MEN1 (0.48) | MEN1KMT2ABLMTHRBRECQL | |
| SCHEMBL10082363 | 0.71 | USP2 (0.73) | MEN1KMT2AMAOBUSP2POLB | |
| SCHEMBL15488854 | 0.71 | MEN1 (0.57) | MEN1KMT2ABLMTHRBRECQL | |
| SCHEMBL12332448 | 0.71 | MEN1 (0.70) | MEN1KMT2ABLMTHRBRECQL | |
| SCHEMBL14533580 | 0.70 | MEN1 (0.54) | MEN1KMT2ABLMTHRBRECQL | |
| SCHEMBL15488855 | 0.70 | MEN1 (0.45) | MEN1KMT2ABLMTHRBRECQL | |
| SCHEMBL14013408 | 0.70 | MEN1 (0.79) | MEN1KMT2ABLMTHRBRECQL | |
| SCHEMBL13525202 | 0.69 | MEN1 (1.00) | MEN1KMT2ABLMTHRBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140127137-A1 | SMMR (SMALL MOLECULE METABOLITE REPORTERS) FOR USE AS IN VIVO GLUCOSE BIOSENSORS | Cercacor Laboratories, Inc (US) | 2014-05-08 | — | — | US | disclosed |
| US-8466286-B2 | SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors | CERCACOR LABORATORIES, INC. (US) | 2013-06-18 | — | — | US | disclosed |
| US-20120052018-A1 | SMMR (SMALL MOLECULE METABOLITE REPORTERS) FOR USE AS IN VIVO GLUCOSE BIOSENSORS | MASIMO LABORATORIES, INC. (US) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140127137-A1 | SMMR (SMALL MOLECULE METABOLITE REPORTERS) FOR USE AS IN VIVO GLUCOSE BIOSENSORS | GCKR, SYMPK, SUCNR1 | MEN1 606/4885KMT2A 3286/4885BLM 2621/4885 |
| US-20120052018-A1 | SMMR (SMALL MOLECULE METABOLITE REPORTERS) FOR USE AS IN VIVO GLUCOSE BIOSENSORS | GCKR, SYMPK, SUCNR1 | MEN1 606/4885KMT2A 3286/4885BLM 2621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.