Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4171284 | 0.81 | CHRNB2 (0.51) | CHRNB2CHRNB4CHRNA3CHRNA4RAB9A | |
| SCHEMBL3111821 | 0.80 | CHRNB2 (0.56) | CHRNB2CHRNB4CHRNA3CHRNA4RAB9A | |
| SCHEMBL7895323 | 0.79 | MAPK8 (0.59) | CHRNB2CHRNB4CHRNA3CHRNA4RAB9A | |
| SCHEMBL10082882 | 0.79 | CHRNB2 (0.52) | CHRNB2CHRNB4CHRNA3CHRNA4RAB9A | |
| SCHEMBL10068161 | 0.78 | RAB9A (0.49) | RAB9ASYKMEN1KMT2AMAPK1 | |
| SCHEMBL4076010 | 0.78 | CHRNB2 (0.51) | CHRNB2CHRNB4CHRNA3CHRNA4SYK | |
| SCHEMBL6361201 | 0.78 | CHRNB2 (0.53) | CHRNB2CHRNB4CHRNA3CHRNA4RAB9A | |
| SCHEMBL5032590 | 0.78 | NR3C2 (0.57) | CHRNB2CHRNB4CHRNA3CHRNA4RAB9A | |
| SCHEMBL10082485 | 0.77 | CHRNB2 (0.50) | CHRNB2CHRNB4CHRNA3CHRNA4RAB9A | |
| SCHEMBL12883344 | 0.77 | CHRNB2 (0.41) | CHRNB2CHRNB4CHRNA3CHRNA4SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119646-B2 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20090258875-A1 | Fungicide Hydroximoyl-Tetrazole Derivatives | BAYER CROPSCIENCE AG (DE) | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258875-A1 | Fungicide Hydroximoyl-Tetrazole Derivatives | HAAO, CYP51A1, CYP8B1 | CHRNB2 4648/4885CHRNB4 4707/4885CHRNA3 4123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.