Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | TOP1 | P11387 | 3/20 | 0.62 |
| ▸ | TOP2A | P11388 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | BLM | P54132 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.57 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10083153 | 0.89 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD | |
| SCHEMBL14656343 | 0.85 | ALDH1A1 (0.80) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD | |
| SCHEMBL26252728 | 0.83 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD | |
| SCHEMBL14399402 | 0.82 | ALDH1A1 (0.80) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD | |
| SCHEMBL12101904 | 0.81 | ALDH1A1 (0.81) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD | |
| SCHEMBL26252732 | 0.79 | ALDH1A1 (0.79) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD | |
| SCHEMBL10082670 | 0.79 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD | |
| SCHEMBL25138200 | 0.79 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD | |
| SCHEMBL18973765 | 0.78 | DGAT1 (0.74) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD | |
| SCHEMBL18595033 | 0.78 | SMN1; SMN2 (0.77) | ALDH1A1SMN1; SMN2TOP1TOP2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097238-B2 | Cell targeting conjugates | PETER MACCALLUM CANCER INSTITUTE (AU) | 2012-01-17 | — | — | US | disclosed |