⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3060004 | 0.74 | — | — | |
| SCHEMBL6136319 | 0.74 | — | — | |
| SCHEMBL29724961 | 0.74 | — | — | |
| SCHEMBL1683940 | 0.70 | — | — | |
| SCHEMBL30829028 | 0.70 | — | — | |
| SCHEMBL8249683 | 0.70 | — | — | |
| SCHEMBL2371788 | 0.70 | — | — | |
| SCHEMBL2977395 | 0.70 | — | — | |
| SCHEMBL29628954 | 0.70 | — | — | |
| SCHEMBL304451 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112500337-B | Synthetic method of 3-bromo-6-chloropyridine formamide | 苏州康润医药有限公司 | 2022-04-12 | — | — | CN | claimed |
| CN-112500337-A | Synthetic method of 3-bromo-6-chloropyridine formamide | 苏州康润医药有限公司 | 2021-03-16 | — | — | CN | claimed |
| CN-115724827-A | Fused ring derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-03-03 | — | — | CN | disclosed |
| CN-112500337-B | Synthetic method of 3-bromo-6-chloropyridine formamide | 苏州康润医药有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-112500337-B | Synthetic method of 3-bromo-6-chloropyridine formamide | 苏州康润医药有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-112500337-A | Synthetic method of 3-bromo-6-chloropyridine formamide | 苏州康润医药有限公司 | 2021-03-16 | — | — | CN | disclosed |
| CN-112500337-A | Synthetic method of 3-bromo-6-chloropyridine formamide | 苏州康润医药有限公司 | 2021-03-16 | — | — | CN | disclosed |
| US-20180333406-A1 | BENZONAPTHYRIDINE COMPOSITIONS AND USES THEREOF | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2018-11-22 | — | — | US | disclosed |
| EP-2440245-B1 | BENZONAPHTHYRIDINE-CONTAINING VACCINES | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2017-12-06 | — | — | EP | disclosed |
| EP-2512478-B1 | HOMOGENEOUS SUSPENSION OF IMMUNOPOTENTIATING COMPOUNDS AND USES THEREOF | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2017-04-19 | — | — | EP | disclosed |
| US-9597326-B2 | Benzonapthyridine compositions and uses thereof | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2017-03-21 | — | — | US | disclosed |
| WO-2011130379-A1 | BENZONAPTHYRIDINE COMPOSITIONS AND USES THEREOF | NOVARTIS AG (CH) | 2011-10-20 | — | — | WO | disclosed |
| WO-2011084549-A1 | HOMOGENEOUS SUSPENSION OF IMMUNOPOTENTIATING COMPOUNDS AND USES THEREOF | NOVARTIS AG (CH) | 2011-07-14 | — | — | WO | disclosed |
| US-20110081365-A1 | COMPOUNDS AND COMPOSITIONS AS TLR ACTIVITY MODULATORS | IRM LLC (BM) | 2011-04-07 | — | — | US | disclosed |
| EP-2268618-A1 | COMPOUNDS AND COMPOSITIONS AS TLR ACTIVITY MODULATORS | IRM LLC (BM) | 2011-01-05 | — | — | EP | disclosed |
| WO-2010144734-A1 | BENZONAPHTHYRIDINE-CONTAINING VACCINES | NOVARTIS AG (CH) | 2010-12-16 | — | — | WO | disclosed |
| WO-2009111337-A1 | COMPOUNDS AND COMPOSITIONS AS TLR ACTIVITY MODULATORS | IRM LLC (BM) | 2009-09-11 | — | — | WO | disclosed |
| US-20080269287-A1 | Substituted Pyridone Derivative | MSD K.K. (JP) | 2008-10-30 | — | — | US | disclosed |
| CN-101111480-A | Substituted pyridone derivative | BANYU PHARMA CO LTD (JP) | 2008-01-23 | — | — | CN | disclosed |
| EP-1820797-A1 | SUBSTITUTED PYRIDONE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-08-22 | — | — | EP | disclosed |