SCHEMBL6136319

SCHEMBL6136319

[O-][n+]1cc(Br)ccc1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL304451 0.74
SCHEMBL6136492 0.74
SCHEMBL4992062 0.74
SCHEMBL6136576 0.74
SCHEMBL1008408 0.74
SCHEMBL11730335 0.72 LMNA (0.43)
SCHEMBL17648125 0.69 HDAC8 (0.31)
SCHEMBL2160030 0.69 PLCG1 (0.31)
SCHEMBL10330647 0.69 IDH1 (0.37)
SCHEMBL18549510 0.67 POLB (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019181645-A1 COMPOUND, PRECURSOR TO COMPOUND, ORGANIC SEMICONDUCTOR MATERIAL INCLUDING COMPOUND, AND ORGANIC ELECTRONIC DEVICE INCLUDING ORGANIC SEMICONDUCTOR MATERIAL 国立大学法人大阪大学 2019-09-26 WO disclosed
WO-2019181646-A1 MACROMOLECULAR COMPOUND, ORGANIC SEMICONDUCTOR MATERIAL INCLUDING MACROMOLECULAR COMPOUND, AND ORGANIC ELECTRONIC DEVICE INCLUDING ORGANIC SEMICONDUCTOR MATERIAL 国立大学法人大阪大学 2019-09-26 WO disclosed
WO-2019078040-A1 COMPOUND, BONDED BODY OF SAME, AND ORGANIC SEMICONDUCTOR MATERIAL 国立大学法人大阪大学 2019-04-25 WO disclosed
US-9675593-B2 Anti-fibrotic pyridinones INTERMUNE, INC. (US) 2017-06-13 US disclosed
US-20170121345-A1 ANTI-FIBROTIC PYRIDINONES GENENTECH, INC. 2017-05-04 US disclosed
US-20160263090-A1 ANTI-FIBROTIC PYRIDINONES GENENTECH, INC. 2016-09-15 US disclosed
US-9359379-B2 Anti-fibrotic pyridinones INTERMUNE, INC. (US) 2016-06-07 US disclosed
US-20140107110-A1 ANTI-FIBROTIC PYRIDINONES GENENTECH, INC. 2014-04-17 US disclosed
EP-1435953-A4 ANTIVESICANT COMPOUNDS AND METHODS OF MAKING AND USING THEREOF US ARMY MED RES MAT COMMAND (US) 2005-05-04 EP disclosed
EP-1435953-A1 ANTIVESICANT COMPOUNDS AND METHODS OF MAKING AND USING THEREOF U.S. Army Medical Research and Materiel Command (US) 2004-07-14 EP disclosed
US-6664280-B2 For decontaminating an area exposed to a vesicant agent; for therapy of prophylaxis or inhibiting injuries induced by a vesicant agent, such as bis-2-chloroethylsulfide (HD) THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY 2003-12-16 US disclosed
US-20030055090-A1 Antivesicant compounds and methods of making and using thereof LG DISPLAY CO., LTD. (KR) 2003-03-20 US disclosed
WO-2003011292-A1 ANTIVESICANT COMPOUNDS AND METHODS OF MAKING AND USING THEREOF U.S. ARMY MEDICAL RESEARCH AND MATERIEL COMMAND (US) 2003-02-13 WO disclosed