Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 8/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10084307 | 1.00 | HDAC1 (0.49) | HDAC1HDAC4HDAC6HDAC3HDAC7 | |
| SCHEMBL1246013 | 0.90 | KDM4E (0.46) | HDAC1HDAC4HDAC6HDAC3HDAC7 | |
| SCHEMBL1246018 | 0.90 | KDM4E (0.46) | HDAC1HDAC4HDAC6HDAC3HDAC7 | |
| SCHEMBL12890836 | 0.90 | KDM4E (0.46) | HDAC1HDAC4HDAC6HDAC3HDAC7 | |
| SCHEMBL1244246 | 0.90 | KDM4E (0.46) | HDAC1HDAC4HDAC6HDAC3HDAC7 | |
| SCHEMBL14036070 | 0.88 | HDAC1 (0.45) | HDAC1HDAC4HDAC6HDAC3HDAC7 | |
| SCHEMBL14036069 | 0.88 | HDAC1 (0.45) | HDAC1HDAC4HDAC6HDAC3HDAC7 | |
| SCHEMBL14035987 | 0.87 | HDAC1 (0.46) | HDAC1HDAC4HDAC6HDAC3HDAC7 | |
| SCHEMBL1245989 | 0.87 | HDAC1 (0.50) | HDAC1HDAC4HDAC6HDAC3HDAC7 | |
| SCHEMBL1244303 | 0.87 | HDAC1 (0.49) | HDAC1HDAC4HDAC6HDAC3HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8268865-B2 | Quaternary alkyl ammonium bacterial efflux pump inhibitors and therapeutic uses thereof | REMPEX PHARMACEUTICALS, INC. (US) | 2012-09-18 | — | — | US | disclosed |
| US-20120165276-A1 | QUATERNARY ALKYL AMMONIUM BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | MPEX PHARMACEUTICALS, INC. (US) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165276-A1 | QUATERNARY ALKYL AMMONIUM BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | ABCB11, ABCC1, SLC47A1 | HDAC1 333/4885HDAC4 470/4885HDAC6 214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.