Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | ADCY1 | Q08828 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL967480 | 0.96 | KDM4E (0.64) | KDM4EMAPTALDH1A1TSHRALOX15 | |
| SCHEMBL1065563 | 0.89 | KDM4E (0.52) | KDM4EMAPTALDH1A1TSHRALOX15 | |
| SCHEMBL968083 | 0.89 | ALDH1A1 (0.54) | KDM4EMAPTALDH1A1TSHRALOX15 | |
| SCHEMBL12920440 | 0.87 | MAPT (0.56) | KDM4EMAPTALDH1A1TSHRHSD17B10 | |
| SCHEMBL3724358 | 0.86 | MAPT (0.54) | KDM4EMAPTALDH1A1TSHRALOX15 | |
| SCHEMBL3666883 | 0.86 | TP53 (0.52) | KDM4EMAPTALDH1A1TSHRALOX15 | |
| SCHEMBL12974156 | 0.85 | TSHR (0.62) | KDM4EMAPTALDH1A1TSHRALOX15 | |
| SCHEMBL1012437 | 0.85 | NPC1 (0.78) | KDM4EMAPTALDH1A1TSHRALOX15 | |
| SCHEMBL966460 | 0.84 | SMN1; SMN2 (0.55) | KDM4EMAPTALDH1A1TSHRALOX15 | |
| SCHEMBL12920429 | 0.84 | TP53 (0.57) | KDM4EMAPTALDH1A1TSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2569311-B1 | AMBIPOLAR SMALL MOLECULE HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | GEORGIA TECH RES INST (US) | 2016-01-13 | — | — | EP | disclosed |
| EP-2569311-B1 | AMBIPOLAR SMALL MOLECULE HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | GEORGIA TECH RES INST (US) | 2016-01-13 | — | — | EP | disclosed |
| US-9133177-B2 | Ambipolar small molecule hosts for phosphorescent guest emitters | GEORGIA TECH RESEARCH CORPORATION (US) | 2015-09-15 | — | — | US | disclosed |
| US-9133177-B2 | Ambipolar small molecule hosts for phosphorescent guest emitters | GEORGIA TECH RESEARCH CORPORATION (US) | 2015-09-15 | — | — | US | disclosed |
| US-9133177-B2 | Ambipolar small molecule hosts for phosphorescent guest emitters | GEORGIA TECH RESEARCH CORPORATION (US) | 2015-09-15 | — | — | US | disclosed |
| EP-2569311-A1 | AMBIPOLAR SMALL MOLECULE HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | Georgia Tech Research Corporation (US) | 2013-03-20 | — | — | EP | disclosed |
| US-20120172556-A1 | POLYMERIZABLE AMBIPOLAR HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | GEORGIA TECH RESEARCH CORPORATION | 2012-07-05 | — | — | US | disclosed |
| US-20120168732-A1 | AMBIPOLAR SMALL MOLECULE HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | GEORGIA TECH RESEARCH CORPORATION (US) | 2012-07-05 | — | — | US | disclosed |
| US-20120168732-A1 | AMBIPOLAR SMALL MOLECULE HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | GEORGIA TECH RESEARCH CORPORATION (US) | 2012-07-05 | — | — | US | disclosed |
| US-20120172556-A1 | POLYMERIZABLE AMBIPOLAR HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | GEORGIA TECH RESEARCH CORPORATION | 2012-07-05 | — | — | US | disclosed |
| US-20120172556-A1 | POLYMERIZABLE AMBIPOLAR HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | GEORGIA TECH RESEARCH CORPORATION | 2012-07-05 | — | — | US | disclosed |
| US-20120168732-A1 | AMBIPOLAR SMALL MOLECULE HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | GEORGIA TECH RESEARCH CORPORATION (US) | 2012-07-05 | — | — | US | disclosed |
| EP-2445905-A1 | POLYMERIZABLE AMBIPOLAR HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | Georgia Tech Research Corporation (US) | 2012-05-02 | — | — | EP | disclosed |
| US-20110009584-A1 | Romp-Polymerizable Electron Transport Materials Based On A Bis-Oxadiazole Moiety | GEORGIA TECH RESEARCH CORPORATION (US) | 2011-01-13 | — | — | US | disclosed |
| US-20110009584-A1 | Romp-Polymerizable Electron Transport Materials Based On A Bis-Oxadiazole Moiety | GEORGIA TECH RESEARCH CORPORATION (US) | 2011-01-13 | — | — | US | disclosed |
| US-20110009584-A1 | Romp-Polymerizable Electron Transport Materials Based On A Bis-Oxadiazole Moiety | GEORGIA TECH RESEARCH CORPORATION (US) | 2011-01-13 | — | — | US | disclosed |
| WO-2010149622-A1 | AMBIPOLAR SMALL MOLECULE HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | GEORGIA TECH RESEARCH CORPORATION (US) | 2010-12-29 | — | — | WO | disclosed |
| WO-2010149618-A1 | POLYMERIC AMBIPOLAR HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | GEORGIA TECH RESEARCH CORPORATION (US) | 2010-12-29 | — | — | WO | disclosed |
| WO-2010149620-A1 | POLYMERIZABLE AMBIPOLAR HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | GEORGIA TECH RESEARCH CORPORATION (US) | 2010-12-29 | — | — | WO | disclosed |
| WO-2009080797-A1 | ROMP-POLYMERIZABLE ELECTRON TRANSPORT MATERIALS BASED ON A BIS-OXADIAZOLE MOIETY | GEORGIA TECH RESEARCH CORPORATION (US) | 2009-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172556-A1 | POLYMERIZABLE AMBIPOLAR HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | OCIAD1, OCIAD2, OXA1L | KDM4E 4762/4885MAPT 940/4885ALDH1A1 1850/4885 |
| US-20120168732-A1 | AMBIPOLAR SMALL MOLECULE HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | OCIAD2, OCIAD1, ORC3 | KDM4E 4027/4885MAPT 2091/4885ALDH1A1 3486/4885 |
| US-20110009584-A1 | Romp-Polymerizable Electron Transport Materials Based On A Bis-Oxadiazole Moiety | SLCO1B3, SLCO4C1, SLCO2B1 | KDM4E 4711/4885MAPT 834/4885ALDH1A1 1377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.