Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12920440 | 0.88 | MAPT (0.56) | TP53ALDH1A1SMN1; SMN2HPGDTSHR | |
| SCHEMBL1008450 | 0.86 | KDM4E (0.64) | TP53ALDH1A1SMN1; SMN2HPGDTSHR | |
| SCHEMBL968083 | 0.86 | ALDH1A1 (0.54) | TP53ALDH1A1SMN1; SMN2HPGDTSHR | |
| SCHEMBL12920429 | 0.85 | TP53 (0.57) | TP53ALDH1A1SMN1; SMN2HPGDTSHR | |
| SCHEMBL1065563 | 0.84 | KDM4E (0.52) | TP53ALDH1A1SMN1; SMN2HPGDTSHR | |
| SCHEMBL3722591 | 0.84 | KDM4E (0.59) | TP53ALDH1A1SMN1; SMN2HPGDTSHR | |
| SCHEMBL3724358 | 0.83 | MAPT (0.54) | TP53ALDH1A1SMN1; SMN2HPGDTSHR | |
| SCHEMBL3668075 | 0.82 | NPC1 (0.53) | TP53ALDH1A1SMN1; SMN2HPGDTSHR | |
| SCHEMBL967480 | 0.81 | KDM4E (0.64) | TP53ALDH1A1SMN1; SMN2HPGDTSHR | |
| SCHEMBL966460 | 0.81 | SMN1; SMN2 (0.55) | TP53ALDH1A1SMN1; SMN2HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2234991-A1 | ROMP-POLYMERIZABLE ELECTRON TRANSPORT MATERIALS BASED ON A BIS-OXADIAZOLE MOIETY | Georgia Tech Research Corporation (US) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009080797-A1 | ROMP-POLYMERIZABLE ELECTRON TRANSPORT MATERIALS BASED ON A BIS-OXADIAZOLE MOIETY | GEORGIA TECH RESEARCH CORPORATION (US) | 2009-07-02 | — | — | WO | disclosed |