SCHEMBL10084643

SCHEMBL10084643

CNC(=O)C(CS)NC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13163781 1.00
SCHEMBL11111449 1.00
SCHEMBL19934701 0.91 BMP1 (0.46)
SCHEMBL21153275 0.91 BMP1 (0.46)
SCHEMBL19934696 0.91 BMP1 (0.46)
SCHEMBL19934754 0.91 BMP1 (0.46)
SCHEMBL21134710 0.91 BMP1 (0.46)
SCHEMBL21135087 0.91 BMP1 (0.46)
SCHEMBL19934743 0.91 BMP1 (0.46)
SCHEMBL19934735 0.91 BMP1 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2981282-B1 GROWTH HORMONE COMPOUND FORMULATION NOVO NORDISK HEALTHCARE AG (CH) 2020-11-04 EP disclosed
EP-2525834-B1 GROWTH HORMONES WITH PROLONGED IN-VIVO EFFICACY NOVO NORDISK HEALTHCARE AG (CH) 2019-07-17 EP disclosed
US-8865126-B2 Vitamin-targeted imaging agents ENDOCYTE, INC. (US) 2014-10-21 US disclosed
US-8834842-B2 Vitamin-targeted imaging agents ENDOCYTE, INC. (US) 2014-09-16 US disclosed
US-20140065068-A1 VITAMIN-TARGETED IMAGING AGENTS ENDOCYTE, INC. (US) 2014-03-06 US disclosed
EP-2280734-B1 FACTOR IX CONJUGATES WITH EXTENDED HALF-LIVES CANTAB BIOPHARMACEUTICALS PATENTS LTD (MT) 2014-02-26 EP disclosed
US-20130237687-A1 VITAMIN-TARGETED IMAGING AGENTS ENDOCYTE, INC. (US) 2013-09-12 US disclosed
WO-2012010516-A1 GROWTH HORMONE CONJUGATES NOVO NORDISK HEALTH CARE AG (CH) 2012-01-26 WO disclosed
US-20110183906-A1 FACTOR IX CONJUGATES WITH EXTENDED HALF-LIVES CELTIC PHARMA PEG LTD. (GB) 2011-07-28 US disclosed
US-20100249027-A1 CRF CONJUGATES WITH EXTENDED HALF-LIVES HENRY WILLIAM 2010-09-30 US disclosed
US-20100222546-A1 METHODS FOR THE PREPARATION OF FUNCTIONALIZED PEPTIDES, PROTEINS AND CARBOHYDRATES AND THEIR CONJUGATES NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2010-09-02 US disclosed
WO-2010057962-A2 CRF CONJUGATES WITH EXTENDED HALF-LIVES NEUTRON LIMITED (BM) 2010-05-27 WO disclosed