Sugi Predict

Sugi Predict / Compounds / SCHEMBL19934743

SCHEMBL19934743

SCHEMBL19934743

CNC(=O)[C@H](CS)NC(=O)[C@H](CS)NC(=O)[C@H](CS)NC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ BMP1 P13497 3/20 0.46
▸ ACE P12821 1/20 0.46
▸ KDM4E B2RXH2 1/20 0.41
▸ MAPT P10636 1/20 0.41
▸ THRB P10828 1/20 0.41
▸ ALOX15 P16050 1/20 0.41
▸ NFKB1 P19838 1/20 0.41
▸ PTGS2 P35354 1/20 0.41
▸ THPO P40225 1/20 0.41
▸ RECQL P46063 1/20 0.41
▸ BLM P54132 1/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.41
▸ MMP9 P14780 6/20 0.37
▸ MMP2 P08253 2/20 0.37
▸ MMP8 P22894 2/20 0.37
▸ MMP1 P03956 7/20 0.35
▸ ENPEP Q07075 2/20 0.34
▸ ANPEP P15144 1/20 0.34
▸ MMP3 P08254 4/20 0.33
▸ FCER2 P06734 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21135087 1.00 BMP1 (0.46) BMP1ACEKDM4EMAPTTHRB
SCHEMBL19934701 1.00 BMP1 (0.46) BMP1ACEKDM4EMAPTTHRB
SCHEMBL19934735 1.00 BMP1 (0.46) BMP1ACEKDM4EMAPTTHRB
SCHEMBL19934696 1.00 BMP1 (0.46) BMP1ACEKDM4EMAPTTHRB
SCHEMBL19934754 1.00 BMP1 (0.46) BMP1ACEKDM4EMAPTTHRB
SCHEMBL19934707 1.00 BMP1 (0.46) BMP1ACEKDM4EMAPTTHRB
SCHEMBL21153275 1.00 BMP1 (0.46) BMP1ACEKDM4EMAPTTHRB
SCHEMBL21134710 1.00 BMP1 (0.46) BMP1ACEKDM4EMAPTTHRB
Hydrochloric Acid SCHEMBL28684194 0.98 BMP1 (0.45) BMP1ACEKDM4EMAPTTHRB
Hydrochloric Acid SCHEMBL28684187 0.98 BMP1 (0.45) BMP1ACEKDM4EMAPTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118178369-A Application of aminothiol compound as cerebral nerve or heart protecting agent 上海科州药物研发有限公司 2024-06-14 — — CN claimed
CN-114072381-B Application of aminothiol compound as cerebral nerve or heart protecting agent 上海科州药物研发有限公司 2024-02-27 — — CN claimed
CN-114072381-A Use of aminothiol compounds as neurocerebroprotective or cardioprotective agents 上海科州药物研发有限公司 2022-02-18 — — CN claimed
CN-118178369-A Application of aminothiol compound as cerebral nerve or heart protecting agent 上海科州药物研发有限公司 2024-06-14 — — CN disclosed
CN-114072381-B Application of aminothiol compound as cerebral nerve or heart protecting agent 上海科州药物研发有限公司 2024-02-27 — — CN disclosed
EP-3508476-B1 AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION SHANGHAI KECHOW PHARMA INC (CN) 2023-11-22 — — EP disclosed
EP-3508476-B1 AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION SHANGHAI KECHOW PHARMA INC (CN) 2023-11-22 — — EP disclosed
EP-3984993-A1 USE OF AMINOTHIOL COMPOUNDS AS CEREBRAL NERVE OR HEART PROTECTIVE AGENT Shanghai Kechow Pharma, Inc. (CN) 2022-04-20 — — EP disclosed
CN-114072381-A Use of aminothiol compounds as neurocerebroprotective or cardioprotective agents 上海科州药物研发有限公司 2022-02-18 — — CN disclosed
US-11008286-B2 Amino mercaptan compound and preparation method therefor and use thereof in protection against radiation SHANGHAI KECHOW PHARMA, INC (CN) 2021-05-18 — — US disclosed
US-11008286-B2 Amino mercaptan compound and preparation method therefor and use thereof in protection against radiation SHANGHAI KECHOW PHARMA, INC (CN) 2021-05-18 — — US disclosed
EP-3508476-A1 AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION Inst Of Radiation Medicine Chinese Acad Of Medical Sciences (CN) 2019-07-10 — — EP disclosed
EP-3508476-A1 AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION Inst Of Radiation Medicine Chinese Acad Of Medical Sciences (CN) 2019-07-10 — — EP disclosed
US-20190202779-A1 AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION SHANGHAI KECHOW PHARMA, INC. (CN) 2019-07-04 — — US disclosed
US-20190202779-A1 AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION SHANGHAI KECHOW PHARMA, INC. (CN) 2019-07-04 — — US disclosed
WO-2018041245-A1 AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION 中国医学科学院放射医学研究所 2018-03-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190202779-A1 AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION MGMT, PRMT8, SULT1A1 BMP1 1779/4885ACE 4638/4885KDM4E 3896/4885
US-11008286-B2 Amino mercaptan compound and preparation method therefor and use thereof in protection against radiation MGMT, GSTA1, PRMT1 BMP1 1926/4885ACE 2519/4885KDM4E 2423/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.