Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 9/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 4/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4467734 | 0.79 | TSHR (0.43) | ADORA2BADORA2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9118472 | 0.69 | KDM4E (0.39) | ADORA2BADORA2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1702032 | 0.69 | TSHR (0.55) | ADORA2BADORA2APKMKDM4EALDH1A1 | |
| SCHEMBL7866286 | 0.67 | ADORA2B (0.79) | ADORA2BADORA2AKDM4EALDH1A1MAPK1 | |
| SCHEMBL1546096 | 0.67 | MAPT (0.49) | ADORA2BADORA2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3297433 | 0.67 | KMT2A (0.54) | ADORA2BADORA2AALDH1A1SMN1; SMN2GLA | |
| SCHEMBL10084476 | 0.67 | ADORA3 (0.49) | ADORA2BKDM4EALDH1A1SMN1; SMN2GLA | |
| SCHEMBL17979387 | 0.67 | MAPT (0.45) | ADORA2BADORA2AKDM4ERXFP1MAPT | |
| SCHEMBL17935736 | 0.65 | APEX1 (0.54) | ADORA2BADORA2AKDM4ESMN1; SMN2GLA | |
| SCHEMBL559878 | 0.65 | MAPT (0.50) | ADORA2BADORA2AKDM4ESMN1; SMN2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004732-A1 | IMIDAZOPYRIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-01-12 | — | — | WO | disclosed |