Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 3/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.39 |
| ▸ | MARK3 | P27448 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | ITK | Q08881 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14271432 | 0.93 | STAT3 (0.47) | STAT3STAT1ACHECYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL29089945 | 0.91 | STAT3 (0.49) | STAT3STAT1ACHEADORA3ADORA2A | |
| SCHEMBL13380379 | 0.88 | STAT3 (0.43) | STAT3STAT1ACHEATP4AATP4B | |
| SCHEMBL14271484 | 0.87 | ACHE (0.43) | STAT3STAT1ACHEADORA3ADORA2A | |
| SCHEMBL14271575 | 0.82 | STAT3 (0.47) | STAT3STAT1ACHEESR1 | |
| SCHEMBL21523873 | 0.81 | STAT3 (0.53) | STAT3STAT1LMNACYP1A2CYP2D6 | |
| SCHEMBL12057389 | 0.81 | STAT3 (0.43) | STAT3STAT1ACHEADORA3ADORA2A | |
| SCHEMBL585086 | 0.81 | STAT3 (0.55) | STAT3STAT1ACHEATP4AATP4B | |
| SCHEMBL12427947 | 0.80 | STAT3 (0.46) | STAT3STAT1ACHE | |
| SCHEMBL14038527 | 0.79 | STAT3 (0.51) | STAT3STAT1LMNACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1768666-B1 | NOVEL USES OF PORPHYRIN COMPOUNDS | DESTINY PHARMA LTD (GB) | 2012-02-15 | — | — | EP | disclosed |