SCHEMBL10085758

SCHEMBL10085758

Cc1ccc(N(c2ccc(C)cc2)c2ccc(-c3c4ccccc4c(-c4ccc(N(c5ccc(C)cc5)c5cccc(C)c5)cc4)c4cc(-c5ccccc5)ccc34)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 2/20 0.39
HSD17B2 P37059 2/20 0.39
ACHE P22303 3/20 0.37
GRIA2 P42262 1/20 0.34
GRIA4 P48058 1/20 0.34
NPSR1 Q6W5P4 3/20 0.33
MAPT P10636 2/20 0.33
PTGS2 P35354 2/20 0.33
KDM4E B2RXH2 1/20 0.33
HSD17B10 Q99714 1/20 0.33
POLB P06746 1/20 0.33
CTDSP1 Q9GZU7 1/20 0.33
NPC1 O15118 1/20 0.33
NTSR1 P30989 1/20 0.33
RAB9A P51151 1/20 0.33
HTT P42858 2/20 0.32
ALDH1A1 P00352 2/20 0.32
HPGD P15428 2/20 0.32
EPHX1 P07099 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9963836 0.97 HSD17B1 (0.41) HSD17B1HSD17B2ACHEGRIA2GRIA4
SCHEMBL9963849 0.97 HSD17B1 (0.41) HSD17B1HSD17B2ACHEGRIA2GRIA4
SCHEMBL9963834 0.93 ACHE (0.41) ACHENPSR1MAPTKDM4EHSD17B10
SCHEMBL9963847 0.92 ACHE (0.42) ACHENPSR1MAPTKDM4EHSD17B10
SCHEMBL9963821 0.92 ACHE (0.39) ACHENPSR1MAPTKDM4ENPC1
SCHEMBL25772296 0.91 HSD17B1 (0.39) HSD17B1HSD17B2ACHENPSR1MAPT
SCHEMBL13615699 0.89 HSD17B1 (0.38) HSD17B1HSD17B2ACHEMAPTNPC1
SCHEMBL13615778 0.89 HSD17B1 (0.35) HSD17B1HSD17B2ACHENPSR1MAPT
SCHEMBL14099714 0.89 ACHE (0.39) ACHENPSR1MAPTKDM4EHSD17B10
SCHEMBL15762771 0.89 ACHE (0.39) ACHENPSR1MAPTKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8147989-B2 OLED device with stabilized green light-emitting layer GLOBAL OLED TECHNOLOGY LLC (US) 2012-04-03 US disclosed
US-8147989-B2 OLED device with stabilized green light-emitting layer GLOBAL OLED TECHNOLOGY LLC (US) 2012-04-03 US disclosed
WO-2010098879-A1 OLED DEVICE WITH STABILZED GREEN LIGHT-EMITTING LAYER GLOBAL OLED TECHNOLOGY LLC. (US) 2010-09-02 WO disclosed
US-20100219748-A1 OLED DEVICE WITH STABILIZED GREEN LIGHT-EMITTING LAYER GLOBAL OLED TECHNOLOGY LLC 2010-09-02 US disclosed
US-20100219748-A1 OLED DEVICE WITH STABILIZED GREEN LIGHT-EMITTING LAYER GLOBAL OLED TECHNOLOGY LLC 2010-09-02 US disclosed