Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 5/20 | 0.68 |
| ▸ | NPY4R | P50391 | 3/20 | 0.68 |
| ▸ | NPY2R | P49146 | 1/20 | 0.68 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.68 |
| ▸ | NTSR1 | P30989 | 9/20 | 0.58 |
| ▸ | NTSR2 | O95665 | 7/20 | 0.58 |
| ▸ | SORT1 | Q99523 | 6/20 | 0.55 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.55 |
| ▸ | NMUR1 | Q9HB89 | 2/20 | 0.55 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.54 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16489150 | 1.00 | NPY1R (0.68) | NPY1RNPY4RNPY2RNPY5RNTSR1 | |
| SCHEMBL30038638 | 0.94 | NPY1R (0.69) | NPY1RNPY4RNPY2RNPY5RNTSR1 | |
| SCHEMBL29973182 | 0.94 | NPY1R (0.69) | NPY1RNPY4RNPY2RNPY5RNTSR1 | |
| SCHEMBL30692366 | 0.90 | NPY1R (0.83) | NPY1RNPY4RNPY2RNPY5RNTSR1 | |
| SCHEMBL29376509 | 0.90 | NPY1R (0.83) | NPY1RNPY4RNPY2RNPY5RNTSR1 | |
| SCHEMBL10085996 | 0.88 | NPY1R (0.58) | NPY1RNPY4RNPY2RNPY5RNTSR1 | |
| SCHEMBL31657713 | 0.87 | NTSR2 (0.62) | NPY1RNPY4RNPY2RNPY5RNTSR1 | |
| SCHEMBL30956237 | 0.86 | NPY1R (0.70) | NPY1RNPY4RNPY2RNPY5RNTSR1 | |
| SCHEMBL10085994 | 0.84 | NPY1R (0.61) | NPY1RNPY4RNPY2RNPY5RNTSR1 | |
| SCHEMBL31307278 | 0.84 | NPY1R (0.64) | NPY1RNPY4RNPY2RNPY5RNTSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040893-A1 | MODIFICATION OF FEEDING BEHAVIOUR | COWLEY MICHAEL (AU) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040893-A1 | MODIFICATION OF FEEDING BEHAVIOUR | GLP1R, NPY4R, NPY1R | NPY1R 3/4885NPY4R 2/4885NPY2R 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.