SCHEMBL29973182

CC[C@H](C)[C@H](N)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O)[C@@H](C)CC

nearest known ligand 0.69

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	NPY1R	P25929	5/20	0.69

▸	NPY2R	P49146	2/20	0.69

▸	NPY4R	P50391	2/20	0.69

▸	NPY5R	Q15761	2/20	0.69

▸	NTSR1	P30989	11/20	0.64

▸	NTSR2	O95665	9/20	0.64

▸	SORT1	Q99523	8/20	0.61

▸	NMUR2	Q9GZQ4	2/20	0.60

▸	NMUR1	Q9HB89	2/20	0.60

▸	MAPK8	P45983	1/20	0.59

▸	MAPK9	P45984	1/20	0.59

▸	MAPK10	P53779	1/20	0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30038638	0.99	NPY1R (0.69)	NPY1RNPY2RNPY4RNPY5RNTSR1
SCHEMBL16489150	0.94	NPY1R (0.68)	NPY1RNPY2RNPY4RNPY5RNTSR1
SCHEMBL10085999	0.94	NPY1R (0.68)	NPY1RNPY2RNPY4RNPY5RNTSR1
SCHEMBL30956237	0.92	NPY1R (0.70)	NPY1RNPY2RNPY4RNPY5RNTSR1
SCHEMBL31657713	0.92	NTSR2 (0.62)	NPY1RNPY2RNPY4RNPY5RNTSR1
SCHEMBL31307278	0.89	NPY1R (0.64)	NPY1RNPY2RNPY4RNPY5RNTSR1
SCHEMBL30607358	0.88	NPY2R (0.69)	NPY1RNPY2RNPY4RNPY5RMAPK8
SCHEMBL31324069	0.88	NTSR1 (0.65)	NPY1RNTSR1NTSR2SORT1
SCHEMBL31324070	0.88	NTSR1 (0.65)	NPY1RNTSR1NTSR2SORT1
SCHEMBL30037824	0.88	NTSR2 (0.73)	NTSR1NTSR2SORT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4067370-A1	HIGH PENETRATION PRODRUG COMPOSITIONS OF PEPTIDES AND PEPTIDE RELATED COMPOUNDS	Yu, Chongxi (US)	2022-10-05	—	—	EP	disclosed