SCHEMBL10085996

SCHEMBL10085996

CC[C@H](C)[C@H](N)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)C(=O)[C@H](CCCNC(=N)N)NN[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)OC

nearest known ligand 0.58

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ NPY1R P25929 10/20 0.58
▸ NPY4R P50391 10/20 0.55
▸ NPY2R P49146 8/20 0.55
▸ NPY5R Q15761 8/20 0.55
▸ NMUR2 Q9GZQ4 5/20 0.55
▸ NMUR1 Q9HB89 5/20 0.55
▸ NTSR1 P30989 2/20 0.51
▸ NTSR2 O95665 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10085994 0.88 NPY1R (0.61) NPY1RNPY4RNPY2RNPY5RNMUR2
SCHEMBL10085999 0.88 NPY1R (0.68) NPY1RNPY4RNPY2RNPY5RNMUR2
SCHEMBL16489150 0.88 NPY1R (0.68) NPY1RNPY4RNPY2RNPY5RNMUR2
SCHEMBL30038638 0.82 NPY1R (0.69) NPY1RNPY4RNPY2RNPY5RNMUR2
SCHEMBL29973182 0.82 NPY1R (0.69) NPY1RNPY4RNPY2RNPY5RNMUR2
SCHEMBL30581211 0.81 NMUR2 (0.62) NPY1RNPY4RNPY2RNPY5RNMUR2
SCHEMBL30956237 0.81 NPY1R (0.70) NPY1RNPY4RNPY2RNPY5RNMUR2
SCHEMBL31351849 0.81 NMUR2 (0.59) NPY1RNPY4RNPY2RNPY5RNMUR2
SCHEMBL29376509 0.80 NPY1R (0.83) NPY1RNPY4RNPY2RNPY5RNMUR2
SCHEMBL30692366 0.80 NPY1R (0.83) NPY1RNPY4RNPY2RNPY5RNMUR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120040893-A1 MODIFICATION OF FEEDING BEHAVIOUR COWLEY MICHAEL (AU) 2012-02-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120040893-A1 MODIFICATION OF FEEDING BEHAVIOUR GLP1R, NPY4R, NPY1R NPY1R 3/4885NPY4R 2/4885NPY2R 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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