Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PRNP | P04156 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | DNA2 | P51530 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2811213 | 0.85 | HTT (0.59) | HTTSMN1; SMN2KEAP1PBRM1KDM4E | |
| SCHEMBL29415445 | 0.85 | HTT (0.59) | HTTSMN1; SMN2KEAP1PBRM1KDM4E | |
| SCHEMBL29363892 | 0.84 | BRPF1 (0.54) | HTTSMN1; SMN2PRNPPBRM1KDM4E | |
| SCHEMBL11471254 | 0.83 | AKR1C3 (0.44) | HTTSMN1; SMN2PRNPALDH1A1MAPT | |
| SCHEMBL21805534 | 0.80 | CDK4 (0.40) | HTTSMN1; SMN2KEAP1KDM4EALDH1A1 | |
| SCHEMBL1271502 | 0.80 | ALDH1A1 (0.58) | HTTKDM4EALDH1A1HPGDNR4A2 | |
| SCHEMBL30088277 | 0.80 | CDK4 (0.40) | HTTSMN1; SMN2KEAP1KDM4EALDH1A1 | |
| SCHEMBL3762044 | 0.80 | KDM4E (0.50) | HTTSMN1; SMN2PRNPKDM4EALDH1A1 | |
| SCHEMBL28685435 | 0.79 | AKR1C3 (0.49) | HTTSMN1; SMN2ALDH1A1HPGDMAPT | |
| SCHEMBL18589537 | 0.79 | CSNK2A2 (0.69) | HTTSMN1; SMN2KEAP1PBRM1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190113842-A1 | RESIST COMPOSITION AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2019-04-18 | — | — | US | disclosed |
| EP-2460787-A1 | Amide compounds and their use as PGE2 antagonists. | Astellas Pharma Inc. (JP) | 2012-06-06 | — | — | EP | disclosed |
| CN-1213029-C | Process for the preparation of (3-cyano-1H-indol-7-yl) (4-(4-fluorophenethyl)piperazin-1-yl)-methanone and salts thereof | MERCH PATENT GMBH (DE) | 2005-08-03 | — | — | CN | disclosed |
| CN-1487923-A | Process for the preparation of (3-cyano-1H-indol-7-yl) (4- (4-fluorophenethyl) piperazin-1-yl) -methanone and salts thereof | Ĭ��ר���ɷ�����˾ | 2004-04-07 | — | — | CN | disclosed |