Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 9/20 | 0.64 |
| ▸ | NPC1 | O15118 | 6/20 | 0.58 |
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.58 |
| ▸ | PLG | P00747 | 5/20 | 0.58 |
| ▸ | PLAT | P00750 | 5/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10082336 | 0.86 | CA1 (0.59) | PLAUNPC1RAB9ACASP3SENP7 | |
| SCHEMBL5676171 | 0.80 | RAB9A (0.63) | NPC1RAB9ACA1CA2CA9 | |
| SCHEMBL15481246 | 0.77 | CA1 (0.70) | NPC1RAB9ACA1CA2CA9 | |
| SCHEMBL30276774 | 0.77 | SNCA (0.54) | CA1CA2CA9 | |
| SCHEMBL2508208 | 0.77 | SNCA (0.54) | CA1CA2CA9 | |
| SCHEMBL28558552 | 0.76 | CA1 (0.69) | NPC1RAB9ACA1CA2CA9 | |
| SCHEMBL14636502 | 0.76 | F2 (0.48) | NPC1RAB9ACA1CA2CA9 | |
| SCHEMBL30497644 | 0.76 | F2 (0.48) | NPC1RAB9ACA1CA2CA9 | |
| SCHEMBL257797 | 0.76 | CA1 (0.68) | NPC1RAB9ACA1CA2CA9 | |
| SCHEMBL14165417 | 0.76 | CA1 (0.68) | NPC1RAB9ACA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8466286-B2 | SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors | CERCACOR LABORATORIES, INC. (US) | 2013-06-18 | — | — | US | disclosed |
| US-20120052018-A1 | SMMR (SMALL MOLECULE METABOLITE REPORTERS) FOR USE AS IN VIVO GLUCOSE BIOSENSORS | MASIMO LABORATORIES, INC. (US) | 2012-03-01 | — | — | US | disclosed |
| US-8029765-B2 | SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors | MASIMO LABORATORIES, INC. (US) | 2011-10-04 | — | — | US | disclosed |
| US-8008088-B2 | SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors | MASIMO LABORATORIES, INC. (US) | 2011-08-30 | — | — | US | disclosed |
| US-8008088-B2 | SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors | MASIMO LABORATORIES, INC. (US) | 2011-08-30 | — | — | US | disclosed |
| US-20090004108-A1 | Smmr (Small Molecule Metabolite Reporters) For Use As In Vivo Glucose Biosensors | MASIMO LABORATORIES, INC. (US) | 2009-01-01 | — | — | US | disclosed |
| US-20090004108-A1 | Smmr (Small Molecule Metabolite Reporters) For Use As In Vivo Glucose Biosensors | MASIMO LABORATORIES, INC. (US) | 2009-01-01 | — | — | US | disclosed |
| US-20070110672-A1 | SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors | CERCACOR LABORATORIES, INC. | 2007-05-17 | — | — | US | disclosed |
| US-20070110672-A1 | SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors | CERCACOR LABORATORIES, INC. | 2007-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070110672-A1 | SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors | GCKR, SYMPK, SUCNR1 | PLAU 4232/4885NPC1 1873/4885RAB9A 4390/4885 |
| US-20120052018-A1 | SMMR (SMALL MOLECULE METABOLITE REPORTERS) FOR USE AS IN VIVO GLUCOSE BIOSENSORS | GCKR, SYMPK, SUCNR1 | PLAU 4232/4885NPC1 1873/4885RAB9A 4390/4885 |
| US-20090004108-A1 | Smmr (Small Molecule Metabolite Reporters) For Use As In Vivo Glucose Biosensors | GCKR, SYMPK, SUCNR1 | PLAU 4232/4885NPC1 1873/4885RAB9A 4390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.