Ethylene Glycol

Ethylene Glycol

SCHEMBL1008646

CC(C)=C(C)C(=O)OCCOC(=O)C(C)=C(C)C.OCCO

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.39
CHRM5 P08912 4/20 0.38
CHRM1 P11229 4/20 0.38
CHRM3 P20309 4/20 0.38
TSHR P16473 4/20 0.34
CHRM2 P08172 3/20 0.34
CHRM4 P08173 3/20 0.34
ALDH1A1 P00352 3/20 0.34
CHRNB2 P17787 2/20 0.34
CHRNA4 P43681 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
PGR P06401 1/20 0.34
HTR1A P08908 1/20 0.34
TBXA2R P21731 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA7 P36544 1/20 0.34
CHRNA10 Q9GZZ6 1/20 0.34
CHRNA9 Q9UGM1 1/20 0.34
GALR3 O60755 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL958243 0.90 TSHR (0.39) THRBCHRM5CHRM1CHRM3TSHR
SCHEMBL11327718 0.87 MEN1 (0.46) THRBCHRM5CHRM1CHRM3TSHR
SCHEMBL976432 0.87 MEN1 (0.46) THRBCHRM5CHRM1CHRM3TSHR
SCHEMBL2017635 0.87 MEN1 (0.46) THRBCHRM5CHRM1CHRM3TSHR
SCHEMBL7456092 0.86 TSHR (0.39) THRBCHRM5CHRM1CHRM3TSHR
SCHEMBL1171604 0.84 TSHR (0.42) CHRM5CHRM1CHRM3TSHRALDH1A1
SCHEMBL860176 0.83 TSHR (0.41) THRBCHRM5CHRM1CHRM3TSHR
SCHEMBL3238710 0.82 TSHR (0.46) TSHRALDH1A1GAAAPEX1
SCHEMBL4428712 0.82 TSHR (0.46) TSHRALDH1A1GAAAPEX1
SCHEMBL129272 0.80 TSHR (0.42) THRBCHRM5CHRM1CHRM3TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2268782-A2 MULTILAYER FRAGRANCE ENCAPSULATION AMCOL INTERNATIONAL CORPORATION (US) 2011-01-05 EP claimed
US-20090258812-A1 MULTILAYER FRAGRANCE ENCAPSULATION AMCOL INTERNATIONAL CORPORATION (US) 2009-10-15 US claimed
WO-2009126960-A2 MULTILAYER FRAGRANCE ENCAPSULATION AMCOL INTERNATIONAL CORPORATION (US) 2009-10-15 WO claimed
US-20020009497-A1 Method of treatment for dermatological disorders and compositions therefor TOBEY RAYMOND E (US) 2002-01-24 US claimed
US-5256400-A Pressurized product delivery systems ADVANCED POLYMER SYSTEMS, INC. (US) 1993-10-26 US claimed
WO-1993010826-A1 PRESSURIZED PRODUCT DELIVERY SYSTEMS ADVANCED POLYMER SYSTEMS, INC. (US) 1993-06-10 WO claimed
EP-0285694-B1 POROUS POLYMERIC BEADS FOR THE DELIVERY OF AN ACTIVE INGREDIENT Advanced Polymer Systems, Inc. (US) 1991-10-30 EP claimed
EP-0285694-A1 Porous polymeric beads for the delivery of an active ingredient Advanced Polymer Systems, Inc. (US) 1988-10-12 EP claimed
US-4690825-A COPOLYMERIZING STYRENE AND DIVINYL BENZENE IN SOLUTION WITH MINERAL OIL; NONCOLLAPSING NETWORK ADVANCED POLYMER SYSTEMS, INC. (US) 1987-09-01 US claimed
US-10709549-B2 Hydrophilic AIOL with bonding SHIFAMED HOLDINGS, LLC (US) 2020-07-14 US disclosed
US-10350057-B2 Hydrophilic AIOL with bonding SHIFAMED HOLDINGS, LLC (US) 2019-07-16 US disclosed
WO-2018215257-A1 METHOD FOR IMPREGNATING POLYMETHYL METHACRYLATE PARTICLES WITH A COLOURING AGENT SENSIENT COSMETIC TECHNOLOGIES (FR) 2018-11-29 WO disclosed
US-20180161152-A1 HYDROPHILIC AIOL WITH BONDING SHIFAMED HOLDINGS, LLC 2018-06-14 US disclosed
US-20170049562-A1 HYDROPHILIC AIOL WITH BONDING SHIFAMED HOLDINGS, LLC 2017-02-23 US disclosed
EP-0285694-A1 Porous polymeric beads for the delivery of an active ingredient Advanced Polymer Systems, Inc. (US) 1988-10-12 EP disclosed
EP-0277211-A1 POLYMERIC CARRIER COMPOSITIONS AND METHODS FOR THEIR PREPARATION AND USE. ADVANCED POLYMER SYSTEMS INC (US) 1988-08-10 EP disclosed
WO-1988001164-A1 POLYMERIC CARRIER COMPOSITIONS AND METHODS FOR THEIR PREPARATION AND USE ADVANCED POLYMER SYSTEMS, INC. (US) 1988-02-25 WO disclosed
US-4690825-A COPOLYMERIZING STYRENE AND DIVINYL BENZENE IN SOLUTION WITH MINERAL OIL; NONCOLLAPSING NETWORK ADVANCED POLYMER SYSTEMS, INC. (US) 1987-09-01 US disclosed
US-4391894-A BASIC DYE REACTED WITH ORGANIC ACID DISSOLVED IN A PHOTOSENSITIVE DIAZO COMPOSITION POLYCHROME CORPORATION (US) 1983-07-05 US disclosed
US-4347300-A CONCURRENT PRODUCTION OF NEGATIVE AND POSITIVE IMAGE; DIAZOTIXZATION; LITHOGRAPHY POLYCHROME CORPORATION (US) 1982-08-31 US disclosed