Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL859851 | 0.94 | THRB (0.42) | TSHRTHRBCHRM5CHRM1CHRM3 | |
| SCHEMBL6812522 | 0.92 | THRB (0.41) | TSHRTHRBCHRM5CHRM1CHRM3 | |
| SCHEMBL12444527 | 0.84 | THRB (0.45) | TSHRTHRBCHRM5CHRM1CHRM3 | |
| Ethylene Glycol SCHEMBL1008646 | 0.83 | THRB (0.39) | TSHRTHRBCHRM5CHRM1CHRM3 | |
| SCHEMBL27859554 | 0.82 | TSHR (0.48) | TSHRTHRBCHRM5CHRM1CHRM3 | |
| SCHEMBL4675894 | 0.80 | TSHR (0.43) | TSHRTHRBCHRM5CHRM1CHRM3 | |
| SCHEMBL3012356 | 0.80 | TSHR (0.43) | TSHRTHRBCHRM5CHRM1CHRM3 | |
| SCHEMBL28417033 | 0.79 | LPAR3 (0.39) | THRBCHRM5CHRM1CHRM3 | |
| SCHEMBL958243 | 0.78 | TSHR (0.39) | TSHRTHRBCHRM5CHRM1CHRM3 | |
| SCHEMBL129272 | 0.78 | TSHR (0.42) | TSHRTHRBCHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8221957-B2 | Planographic printing plate precursor and printing method using the same | FUJIFILM CORPORATION (JP) | 2012-07-17 | — | — | US | disclosed |
| US-8142983-B2 | Lithographic printing plate precursor and method of lithographic printing | FUJIFILM CORPORATION (JP) | 2012-03-27 | — | — | US | disclosed |