Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.56 |
| ▸ | AKT1 | P31749 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10315779 | 1.00 | ADRB2 (0.56) | ADRB2AKT1HPGDGAASMN1; SMN2 | |
| SCHEMBL16984369 | 0.85 | TYR (0.41) | ADRB2AKT1HPGDGAASMN1; SMN2 | |
| SCHEMBL6260990 | 0.81 | ADRB2 (0.50) | ADRB2AKT1HPGDGAASMN1; SMN2 | |
| SCHEMBL19286210 | 0.80 | ADRB2 (0.54) | ADRB2AKT1HPGDGAASMN1; SMN2 | |
| SCHEMBL2669157 | 0.78 | ADRB2 (0.52) | ADRB2AKT1HPGDGAASMN1; SMN2 | |
| SCHEMBL8353370 | 0.78 | ADRB2 (0.52) | ADRB2AKT1HPGDGAASMN1; SMN2 | |
| SCHEMBL178627 | 0.78 | ADRB2 (0.52) | ADRB2AKT1HPGDGAASMN1; SMN2 | |
| SCHEMBL8278972 | 0.78 | SMN1; SMN2 (0.41) | SMN1; SMN2TDP1LMNA | |
| SCHEMBL21836282 | 0.77 | MEN1 (0.52) | ADRB2AKT1TSHRTDP1SLC6A2 | |
| SCHEMBL21836281 | 0.77 | MEN1 (0.52) | ADRB2AKT1TSHRTDP1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3689886-A1 | BCL-2/BCL-XL INHIBITORS AND THEIR USE IN THE TREATMENT OF CANCER | The Regents of The University of Michigan (US) | 2020-08-05 | — | — | EP | disclosed |
| WO-2020140956-A1 | PROCESS FOR PREPARING SULFONAMIDE COMPOUNDS | ASCENTAGE PHARMA (SUZHOU) CO., LTD. (CN) | 2020-07-09 | — | — | WO | disclosed |
| US-8124634-B2 | CB1 receptor modulators | 7TM PHARMA A/S (DK) | 2012-02-28 | — | — | US | disclosed |
| US-20100010061-A1 | CB1 RECEPTOR MODULATORS | 7TM PHARMA A/S (DK) | 2010-01-14 | — | — | US | disclosed |
| US-20070197522-A1 | Dpp-iv inhibitors | SANTHERA PHARMACEUTICALS (SCHWEIZ) GMBH (CH) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197522-A1 | Dpp-iv inhibitors | DPP7, DPP4, DPP3 | ADRB2 813/4885AKT1 3640/4885HPGD 3780/4885 |
| US-20100010061-A1 | CB1 RECEPTOR MODULATORS | CNR1, CNR2, GPR6 | ADRB2 171/4885AKT1 2235/4885HPGD 4218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.