Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL178627 | 1.00 | ADRB2 (0.52) | ADRB2ALDH1A1FFAR2SLC6A4HTR2A | |
| SCHEMBL2669157 | 1.00 | ADRB2 (0.52) | ADRB2ALDH1A1FFAR2SLC6A4HTR2A | |
| Hydrochloric Acid SCHEMBL20303159 | 0.98 | ADRB2 (0.50) | ADRB2ALDH1A1FFAR2SLC6A4HTR2A | |
| Hydrochloric Acid SCHEMBL20303161 | 0.98 | ADRB2 (0.50) | ADRB2ALDH1A1FFAR2SLC6A4HTR2A | |
| SCHEMBL2669165 | 0.84 | ALDH1A1 (0.54) | ALDH1A1GAASMN1; SMN2HIF1ALMNA | |
| SCHEMBL19286210 | 0.82 | ADRB2 (0.54) | ADRB2ALDH1A1FFAR2HPGDGAA | |
| SCHEMBL28277737 | 0.82 | ADRB2 (0.54) | ADRB2ALDH1A1FFAR2HPGDGAA | |
| SCHEMBL11633101 | 0.78 | ADRB2 (0.56) | ADRB2ALDH1A1FFAR2HPGDGAA | |
| SCHEMBL10087172 | 0.78 | ADRB2 (0.56) | ADRB2ALDH1A1FFAR2SLC6A4HPGD | |
| SCHEMBL10315779 | 0.78 | ADRB2 (0.56) | ADRB2ALDH1A1FFAR2SLC6A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250129067-A1 | PLATELET-DERIVED GROWTH FACTOR RECEPTOR (PDGFR) ALPHA INHIBITORS AND USES THEREOF | PROGENTOS THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | US | disclosed |
| CN-118475580-A | Platelet-derived growth factor receptor (PDGFR) alpha inhibitors and uses thereof | 普罗根托斯治疗公司 | 2024-08-09 | — | — | CN | disclosed |
| US-20220281850-A1 | BISAMIDE SARCOMERE ACTIVATING COMPOUNDS AND USES THEREOF | AMGEN INC. | 2022-09-08 | — | — | US | disclosed |
| US-11123355-B2 | Antiviral benzyl-amine phosphodiamide compounds | IDENIX PHARMACEUTICALS LLC (US) | 2021-09-21 | — | — | US | disclosed |
| US-20200223829-A1 | BISAMIDE SARCOMERE ACTIVATING COMPOUNDS AND USES THEREOF | AMGEN INC. | 2020-07-16 | — | — | US | disclosed |
| US-20200223830-A1 | BISAMIDE SARCOMERE ACTIVATING COMPOUNDS AND USES THEREOF | CYTOKINETICS, INC. | 2020-07-16 | — | — | US | disclosed |
| US-20190321380-A1 | ANTIVIRAL BENZYL-AMINE PHOSPHODIAMIDE COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2019-10-24 | — | — | US | disclosed |
| EP-1404704-B9 | BRIDGED BICYCLIC SERINE PROTEASE INHIBITORS | VERTEX PHARMA (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2007020502-A2 | CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PHARMACIA & UPJOHN COMPANY LLC (US) | 2007-02-22 | — | — | WO | disclosed |
| WO-2003035060-A1 | INHIBITORS OF SERINE PROTEASE, PARTICULARLY HEPATITIS C VIRUS NS3-NS4A PROTEASE, INCORPORATING A FUSED RING SYSTEM | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2003-05-01 | — | — | WO | disclosed |
| WO-2003006490-A1 | BRIDGED BICYCLIC SERINE PROTEASE INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2003-01-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200223830-A1 | BISAMIDE SARCOMERE ACTIVATING COMPOUNDS AND USES THEREOF | TNNI3, TNNT2, TNNC1 | ADRB2 397/4885ALDH1A1 3628/4885FFAR2 3081/4885 |
| US-20190321380-A1 | ANTIVIRAL BENZYL-AMINE PHOSPHODIAMIDE COMPOUNDS | TYMP, PNP, POLI | ADRB2 3076/4885ALDH1A1 2794/4885FFAR2 4614/4885 |
| US-11123355-B2 | Antiviral benzyl-amine phosphodiamide compounds | TYMP, PNP, POLI | ADRB2 3076/4885ALDH1A1 2794/4885FFAR2 4614/4885 |
| US-20200223829-A1 | BISAMIDE SARCOMERE ACTIVATING COMPOUNDS AND USES THEREOF | TNNI3, TNNT2, TNNC1 | ADRB2 397/4885ALDH1A1 3628/4885FFAR2 3081/4885 |
| US-20220281850-A1 | BISAMIDE SARCOMERE ACTIVATING COMPOUNDS AND USES THEREOF | TNNI3, TNNT2, TNNC1 | ADRB2 397/4885ALDH1A1 3628/4885FFAR2 3081/4885 |
| US-20250129067-A1 | PLATELET-DERIVED GROWTH FACTOR RECEPTOR (PDGFR) ALPHA INHIBITORS AND USES THEREOF | PDGFRB, PDGFRA, PDGFA | ADRB2 2485/4885ALDH1A1 3250/4885FFAR2 935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.