Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 9/20 | 0.52 |
| ▸ | CA2 | P00918 | 9/20 | 0.52 |
| ▸ | CA9 | Q16790 | 9/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | F11 | P03951 | 3/20 | 0.46 |
| ▸ | LPL | P06858 | 4/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20911812 | 0.86 | CA1 (0.53) | CA1CA2CA9CA12CA3 | |
| SCHEMBL15985342 | 0.86 | CA1 (0.53) | CA1CA2CA9CA12CA3 | |
| SCHEMBL16014788 | 0.86 | CA1 (0.48) | CA1CA2CA9CA12CA3 | |
| SCHEMBL5618327 | 0.85 | CA1 (0.52) | CA1CA2CA9CA12CA3 | |
| SCHEMBL25673218 | 0.85 | CA1 (0.50) | CA1CA2CA9CA12CA3 | |
| SCHEMBL27150949 | 0.84 | CA1 (0.49) | CA1CA2CA9CA12CA3 | |
| SCHEMBL25388983 | 0.84 | TP53 (0.57) | CA1CA2CA9CA12CA3 | |
| SCHEMBL3323634 | 0.82 | HPGD (0.55) | CA1CA2CA9CA12CA3 | |
| SCHEMBL2698620 | 0.82 | RAB9A (0.52) | CA1CA2CA9CA12CA3 | |
| SCHEMBL15981335 | 0.82 | PTPN1 (0.58) | CA1CA2CA9CA12CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016115360-A1 | C-MYC LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | COFERON, INC. (US) | 2016-07-21 | — | — | WO | disclosed |
| WO-2015081280-A1 | BROMODOMAIN LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION | COFERON, INC. (US) | 2015-06-04 | — | — | WO | disclosed |
| US-20140243286-A1 | BROMODOMAIN LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | COFERON, INC. (US) | 2014-08-28 | — | — | US | disclosed |
| US-20140243286-A1 | BROMODOMAIN LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | COFERON, INC. (US) | 2014-08-28 | — | — | US | disclosed |
| EP-2581382-A2 | Radiolabeled compounds and compositions, their precursors and methods for their production | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2013-04-17 | — | — | EP | disclosed |
| US-8114381-B2 | Radiolabeled compounds and compositions, their precursors and methods for their production | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2012-02-14 | — | — | US | disclosed |
| US-8114381-B2 | Radiolabeled compounds and compositions, their precursors and methods for their production | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2012-02-14 | — | — | US | disclosed |
| US-20080038191-A1 | Radiolabeled Compounds And Compositions, Their Precursors And Methods For Their Production | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2008-02-14 | — | — | US | disclosed |
| US-20080038191-A1 | Radiolabeled Compounds And Compositions, Their Precursors And Methods For Their Production | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2008-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080038191-A1 | Radiolabeled Compounds And Compositions, Their Precursors And Methods For Their Production | GMNN, MEN1, NCLN | CA1 441/4885CA2 1568/4885CA9 391/4885 |
| US-20140243286-A1 | BROMODOMAIN LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | BRDT, BRD4, BRD1 | CA1 2152/4885CA2 3650/4885CA9 4757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.