Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.60 |
| ▸ | MMP2 | P08253 | 2/20 | 0.57 |
| ▸ | MMP7 | P09237 | 1/20 | 0.57 |
| ▸ | MMP9 | P14780 | 1/20 | 0.57 |
| ▸ | MMP12 | P39900 | 1/20 | 0.57 |
| ▸ | MMP13 | P45452 | 1/20 | 0.57 |
| ▸ | ACE | P12821 | 5/20 | 0.56 |
| ▸ | CPA1 | P15085 | 3/20 | 0.56 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CPA2 | P48052 | 1/20 | 0.54 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.54 |
| ▸ | MMP3 | P08254 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19762064 | 0.89 | KMT2A (0.55) | MMEMMP2CPA1TSHRCPA2 | |
| SCHEMBL19762061 | 0.89 | ALDH1A1 (0.66) | TSHR | |
| SCHEMBL2606643 | 0.89 | ALDH1A1 (0.66) | TSHR | |
| SCHEMBL21261666 | 0.89 | MME (0.58) | MMEMMP2MMP7MMP9MMP12 | |
| SCHEMBL21244271 | 0.89 | MME (0.58) | MMEMMP2MMP7MMP9MMP12 | |
| SCHEMBL21244270 | 0.89 | MME (0.58) | MMEMMP2MMP7MMP9MMP12 | |
| SCHEMBL17948648 | 0.88 | CPA1 (0.63) | MMEMMP2MMP7MMP9MMP12 | |
| SCHEMBL7382794 | 0.88 | ACE (0.74) | MMEACECPA1ACE2 | |
| SCHEMBL17948645 | 0.88 | LTA4H (0.58) | MMEMMP2MMP7MMP9MMP12 | |
| Hydrochloric Acid SCHEMBL19741504 | 0.87 | LTA4H (0.57) | MMEMMP2MMP7MMP9MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8207127-B2 | Compounds for enzyme inhibition | ONYX TECHNOLOGIES, INC. (US) | 2012-06-26 | — | — | US | disclosed |