Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4289629 | 0.79 | ALDH1A1 (0.36) | ALDH1A1TDP1 | |
| SCHEMBL4289622 | 0.79 | ALDH1A1 (0.36) | ALDH1A1TDP1 | |
| SCHEMBL14940213 | 0.79 | ALDH1A1 (0.36) | ALDH1A1TDP1 | |
| SCHEMBL14134967 | 0.79 | ALDH1A1 (0.36) | ALDH1A1TDP1 | |
| SCHEMBL18654231 | 0.77 | CHRM2 (0.31) | — | |
| SCHEMBL10419624 | 0.77 | — | — | |
| SCHEMBL4466560 | 0.77 | — | — | |
| SCHEMBL24240747 | 0.76 | — | — | |
| SCHEMBL10033827 | 0.76 | — | — | |
| SCHEMBL64601 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148324-B2 | Aldolases, nucleic acids encoding them; improving thermal stability of enzyme; biosynthesis of atorvastatin, rosuvastatin, fluvastatin starting from e.g. acetaldehyde and chloroacetaldehyde, using enzyme 2-deoxyribose-5-phosphate aldolase (DERA) to form pyran intermediate | VERENIUM CORPORATION (US) | 2012-04-03 | — | — | US | disclosed |
| US-20080289056-A1 | CHEMOENZYMATIC METHODS FOR THE SYNTHESIS OF STATINS AND STATIN INTERMEDIATES | VERENIUM CORPORATION (US) | 2008-11-20 | — | — | US | disclosed |