⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13902909 | 0.81 | — | — | |
| SCHEMBL697399 | 0.81 | — | — | |
| SCHEMBL10580165 | 0.81 | — | — | |
| SCHEMBL10580174 | 0.81 | — | — | |
| SCHEMBL60921 | 0.81 | — | — | |
| SCHEMBL11892692 | 0.81 | — | — | |
| SCHEMBL10087481 | 0.77 | ALDH1A1 (0.35) | — | |
| SCHEMBL18654231 | 0.77 | CHRM2 (0.31) | — | |
| SCHEMBL8681978 | 0.76 | — | — | |
| SCHEMBL3807866 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7473788-B2 | Analogs of terpene trilactones from Ginkgo biloba and related compounds and uses thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2009-01-06 | — | — | US | disclosed |
| US-20070098632-A1 | Analogs of terpene trilactones from ginkgo biloba and related compounds and uses thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2007-05-03 | — | — | US | disclosed |
| US-7145021-B2 | Analogs of terpene trilactones from Ginkgo biloba and related compounds and uses thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2006-12-05 | — | — | US | disclosed |
| US-20030225052-A1 | Analogs of terpene trilactones from Ginkgo biloba and related compounds and uses thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2003-12-04 | — | — | US | disclosed |