SCHEMBL1008876

SCHEMBL1008876

N#CCc1c(F)cccc1F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
KDM4E B2RXH2 4/20 0.38
TDP1 Q9NUW8 1/20 0.38
GAA P10253 1/20 0.36
EGFR P00533 1/20 0.36
SRC P12931 1/20 0.36
ALDH1A1 P00352 3/20 0.35
ENPP2 Q13822 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ATM Q13315 1/20 0.34
BCAT1 P54687 1/20 0.33
CUL4A Q13619 1/20 0.33
MMP3 P08254 1/20 0.33
CA12 O43570 1/20 0.33
CA2 P00918 1/20 0.33
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3059521 0.85 MAPT (0.37) TAAR1MEN1KMT2AMAPTHPGD
SCHEMBL29464291 0.85 TAAR1 (0.55) TAAR1MEN1KMT2AMAPTKDM4E
SCHEMBL31454642 0.85 MEN1 (0.34) TAAR1MEN1KMT2AMAPTHPGD
SCHEMBL20249844 0.85 ACHE (0.43) TAAR1MEN1KMT2AMAPTHPGD
SCHEMBL958644 0.85 TAAR1 (0.55) TAAR1MEN1KMT2AMAPTKDM4E
SCHEMBL31459480 0.85 ACHE (0.43) TAAR1MEN1KMT2AMAPTHPGD
SCHEMBL13185299 0.85 MEN1 (0.37) TAAR1MEN1KMT2AMAPTHPGD
SCHEMBL534442 0.85 EED (0.37) TAAR1MEN1KMT2AMAPTHPGD
SCHEMBL22904169 0.85 MPO (0.39) TAAR1MEN1KMT2AMAPTHPGD
SCHEMBL23645662 0.82 HPGD (0.36) TAAR1MEN1KMT2AMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 240 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115651923-B Novel detection method for sphingomyelin transport 杭州师范大学 2024-07-26 CN claimed
CN-115651923-A Novel detection method for sphingomyelin transportation 杭州师范大学 2023-01-31 CN claimed
EP-4004186-A1 METHOD OF OBTAINING MITOCHONDRIA FROM CELLS AND OBTAINED MITOCHONDRIA LUCA Science Inc. (JP) 2022-06-01 EP claimed
CN-110746322-A N- [ 3-chloro-4- (1,1, 2-trifluoro-2-trifluoromethoxy-ethyl) -phenyl ] -2, 6-difluoro-benzamidine, preparation method and application 江苏艾科姆检测有限公司 2020-02-04 CN claimed
WO-2025264585-A1 DETECTION OF CANCER BY LIQUID BIOPSY AQTUAL, INC. (US) 2025-12-26 WO disclosed
EP-4630464-A1 FUNCTIONALIZED AND NON-FUNCTIONALIZED AMPHIPHILIC POLYMERS BASED ON POLYACRYLIC ACID FOR THE SOLUBILIZATION, ISOLATION AND MOLECULAR LABELLING OF MEMBRANE PROTEINS IN AQUEOUS MEDIA Cube Biotech GmbH (DE) 2025-10-15 EP disclosed
US-20250163039-A1 HETEROAROMATIC COMPOUNDS FOR THE TREATMENT OF CANCER BOEHRINGER INGELHEIM INT (DE) 2025-05-22 US disclosed
WO-2025101881-A1 HETEROATOM CONTAINING PEPTIDOMIMETICS TARGETING VIRAL PROTEASES EMORY UNIVERSITY (US) 2025-05-15 WO disclosed
CN-119874565-A Mono cyano diaryl ethylene preparation method of class compound 常州大学 2025-04-25 CN disclosed
US-20250099478-A1 PLASMA KALLIKREIN INHIBITORS MERCK SHARP & DOHME LLC (US) 2025-03-27 US disclosed
WO-2025059080-A1 METHODS OF DETECTING AUTOIMMUNE CONDITIONS AQTUAL, INC. (US) 2025-03-20 WO disclosed
EP-4469458-A1 PLASMA KALLIKREIN INHIBITORS Merck Sharp & Dohme LLC (US) 2024-12-04 EP disclosed
US-5098922-A Anticonvulsants CIBA-GEIGY CORPORATION (US) 1992-03-24 US disclosed
US-5095018-A Anticonvulsants BURROUGHS WELLCOME CO. (US) 1992-03-10 US disclosed
EP-0459285-A1 Ortho-substituted benzyl esters of cyclopropane carboxylic acids BASF Aktiengesellschaft (DE) 1991-12-04 EP disclosed
US-5045556-A Aralkyl-4H-1,2,4-triazole derivatives CIBA-GEIGY CORPORATION (US) 1991-09-03 US disclosed
EP-0402096-A2 Anticonvulsant pyrazines THE WELLCOME FOUNDATION LIMITED (GB) 1990-12-12 EP disclosed
US-4920116-A ANTIARRHYTHMIA AGENTS SCHERING A.G. (DE) 1990-04-24 US disclosed
EP-0324791-A1 ARYL-N-AMINOALKYL-4-(SULFONAMIDO)BENZAMIDES, ANTIARRHYTMIC AGENTS AND COMPOSITIONS THEREOF. SCHERING AG (DE) 1989-07-26 EP disclosed
WO-1988002362-A1 ARYL-N-AMINOALKYL-4-(SULFONAMIDO)BENZAMIDES, ANTIARRHYTMIC AGENTS AND COMPOSITIONS THEREOF SCHERING AKTIENGESELLSCHAFT (DE) 1988-04-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250163039-A1 HETEROAROMATIC COMPOUNDS FOR THE TREATMENT OF CANCER NRAS, KRAS, RB1 TAAR1 2291/4885MEN1 428/4885KMT2A 2424/4885
US-20250099478-A1 PLASMA KALLIKREIN INHIBITORS KLKB1, SERPINE1, KLK5 TAAR1 3497/4885MEN1 1370/4885KMT2A 1905/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.