Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.52 |
| ▸ | PGR | P06401 | 5/20 | 0.46 |
| ▸ | AR | P10275 | 4/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.46 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SHBG | P04278 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4207162 | 1.00 | CYP19A1 (0.52) | CYP19A1PGRARNR3C2SERPINA6 | |
| SCHEMBL10089005 | 0.91 | PGR (0.55) | CYP19A1PGRARNR3C2SERPINA6 | |
| SCHEMBL4210662 | 0.91 | PGR (0.55) | CYP19A1PGRARNR3C2SERPINA6 | |
| SCHEMBL4102539 | 0.87 | CYP19A1 (0.48) | CYP19A1PGRARNR3C2SERPINA6 | |
| SCHEMBL14009902 | 0.86 | SERPINA6 (0.45) | CYP19A1PGRARNR3C2SERPINA6 | |
| SCHEMBL4209999 | 0.81 | CYP19A1 (0.47) | CYP19A1PGRARNR3C2SERPINA6 | |
| SCHEMBL14009969 | 0.80 | CYP19A1 (0.56) | CYP19A1PGRARNR3C2SERPINA6 | |
| SCHEMBL10089006 | 0.80 | AR (0.49) | CYP19A1PGRARNR3C2SERPINA6 | |
| SCHEMBL4208956 | 0.80 | AR (0.49) | CYP19A1PGRARNR3C2SERPINA6 | |
| SCHEMBL4217242 | 0.80 | AR (0.49) | CYP19A1PGRARNR3C2SERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8207150-B2 | 17β-cyano-19-nor-androst-4-ene derivative, its use and medicaments comprising the derivative | Bayer Pharma AG (DE) | 2012-06-26 | — | — | US | disclosed |
| US-20090048217-A1 | 17Beta-CYANO-19-NOR-ANDROST-4-ENE DERIVATIVE, ITS USE AND MEDICAMENTS COMPRISING THE DERIVATIVE | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048217-A1 | 17Beta-CYANO-19-NOR-ANDROST-4-ENE DERIVATIVE, ITS USE AND MEDICAMENTS COMPRISING THE DERIVATIVE | HSD17B11, HSD17B7, NR5A1 | CYP19A1 14/4885PGR 87/4885AR 109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.