Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14094425 | 0.96 | CYP3A4 (0.55) | CYP3A4ABCB11ADRA2BOPRD1SCN5A | |
| SCHEMBL18309253 | 0.96 | CYP3A4 (0.55) | CYP3A4ABCB11ADRA2BOPRD1SCN5A | |
| SCHEMBL10049486 | 0.85 | TSHR (0.42) | CYP3A4OPRD1TSHRALDH1A1TDP1 | |
| SCHEMBL16132834 | 0.85 | TSHR (0.51) | CYP3A4ABCB11ADRA2BOPRD1SCN5A | |
| SCHEMBL14022183 | 0.84 | ESR1 (0.64) | CYP3A4TSHRALDH1A1TDP1ESR1 | |
| SCHEMBL1789210 | 0.83 | CA1 (0.59) | CYP3A4TSHRALDH1A1TDP1ESR1 | |
| SCHEMBL9969969 | 0.83 | TSHR (0.64) | CYP3A4ABCB11ADRA2BOPRD1SCN5A | |
| SCHEMBL14565941 | 0.82 | THRB (0.42) | CYP3A4TSHRALDH1A1TDP1ESR1 | |
| SCHEMBL25784268 | 0.82 | THRB (0.44) | CYP3A4TSHRALDH1A1TDP1ESR1 | |
| SCHEMBL10033550 | 0.82 | CYP3A4 (0.43) | CYP3A4ABCB11ADRA2BOPRD1SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160339730-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR, MANUFACTURING METHOD THEREFOR, PLATE MANUFACTURING METHOD FOR LITHOGRAPHIC PRINTING PLATE, AND PRINTING METHOD | FUJIFILM CORPORATION (JP) | 2016-11-24 | — | — | US | disclosed |
| US-20120160118-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD | FUJIFILM CORPORATION (JP) | 2012-06-28 | — | — | US | disclosed |
| US-20080199804-A1 | Including free radical binder polymer containing functional group having dipole moment of 3.8 debye; laser computer controlled direct plate making without alkali development; sensitivity, printing durability | FUJIFILM CORPORATION (JP) | 2008-08-21 | — | — | US | disclosed |