SCHEMBL10089281

SCHEMBL10089281

C=C(C)c1cc(CN(Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)c2ccc(Nc3ccc(CC(C)CC(C)(C)C)cc3)cc2)cc(C(C)(C)C)c1O

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
GAA P10253 2/20 0.34
LMNA P02545 1/20 0.34
TSHR P16473 1/20 0.34
KDM4E B2RXH2 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
MAPK1 P28482 1/20 0.32
HTT P42858 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13180497 1.00 ALDH1A1 (0.34) ALDH1A1GAALMNATSHRKDM4E
SCHEMBL12889979 1.00 ALDH1A1 (0.34) ALDH1A1GAALMNATSHRKDM4E
SCHEMBL2807214 0.95 ALDH1A1 (0.30) ALDH1A1GAALMNATSHR
SCHEMBL9912698 0.91 ALDH1A1 (0.41) ALDH1A1GAALMNATSHRKDM4E
SCHEMBL2808713 0.91 ALDH1A1 (0.41) ALDH1A1GAALMNATSHRKDM4E
SCHEMBL9912697 0.91 ALDH1A1 (0.41) ALDH1A1GAALMNATSHRKDM4E
SCHEMBL9912713 0.87 GAA (0.37) ALDH1A1GAALMNATSHRKDM4E
SCHEMBL9912714 0.85 EGFR (0.32)
SCHEMBL13180529 0.84 GAA (0.42) ALDH1A1GAALMNATSHRKDM4E
SCHEMBL13406908 0.84 GAA (0.42) ALDH1A1GAALMNATSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120004150-A1 Lubricant Oil Compositions POLNOX CORPORATION 2012-01-05 US disclosed
US-7799948-B2 stabilizers for inhibiting oxidation in organic materials, lubricants and petroleum based products, plastics and elastomers, cosmetics, foods and cooking oils POLNOX CORPORATION (US) 2010-09-21 US disclosed
US-7705075-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2010-04-27 US disclosed
US-20080293856-A1 Stabilized polyolefin compositions POLNOX CORPORATION 2008-11-27 US disclosed
US-20070161522-A1 Lubricant oil compositions POLNOX CORPORATION 2007-07-12 US disclosed