Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HMGCR | P04035 | 2/20 | 0.34 |
| ▸ | GSR | P00390 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9912698 | 1.00 | ALDH1A1 (0.41) | ALDH1A1GAATSHRLMNAMAPK1 | |
| SCHEMBL2808713 | 1.00 | ALDH1A1 (0.41) | ALDH1A1GAATSHRLMNAMAPK1 | |
| SCHEMBL9912713 | 0.95 | GAA (0.37) | ALDH1A1GAATSHRLMNAMAPK1 | |
| SCHEMBL13180497 | 0.91 | ALDH1A1 (0.34) | ALDH1A1GAATSHRLMNAMAPK1 | |
| SCHEMBL12889979 | 0.91 | ALDH1A1 (0.34) | ALDH1A1GAATSHRLMNAMAPK1 | |
| SCHEMBL10089281 | 0.91 | ALDH1A1 (0.34) | ALDH1A1GAATSHRLMNAMAPK1 | |
| SCHEMBL12890045 | 0.89 | ALDH1A1 (0.39) | ALDH1A1GAATSHRLMNAMAPK1 | |
| SCHEMBL2807214 | 0.86 | ALDH1A1 (0.30) | ALDH1A1GAATSHRLMNA | |
| SCHEMBL2785231 | 0.86 | ALDH1A1 (0.36) | ALDH1A1GAATSHRLMNAMAPK1 | |
| SCHEMBL2788691 | 0.86 | ALDH1A1 (0.36) | ALDH1A1GAATSHRLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9523060-B2 | Lubricant oil compositions | POLNOX CORPORATION (US) | 2016-12-20 | — | — | US | disclosed |
| US-9388120-B2 | Nitrogen and hindered phenol containing dual functional macromolecular antioxidants: synthesis, performances and applications | POLNOX CORPORATION (US) | 2016-07-12 | — | — | US | disclosed |
| US-20150159109-A1 | Lubricant Oil Compositions | POLNOX CORPORATION | 2015-06-11 | — | — | US | disclosed |
| US-8927472-B2 | Lubricant oil compositions | POLNOX CORPORATION (US) | 2015-01-06 | — | — | US | disclosed |
| US-20140316163-A1 | NITROGEN AND HINDERED PHENOL CONTAINING DUAL FUNCTIONAL MACROMOLECULAR ANTIOXIDANTS: SYNTHESIS, PERFORMANCES AND APPLICATIONS | POLNOX CORPORATION (US) | 2014-10-23 | — | — | US | disclosed |
| US-20130130955-A1 | LUBRICANT OIL COMPOSITIONS | POLNOX CORPORATION (US) | 2013-05-23 | — | — | US | disclosed |
| US-20120142968-A1 | Nitrogen and Hindered Phenol Containing Dual Functional Macromolecular Antioxidants: Synthesis, Performances and Applications | POLNOX CORPORATION (US) | 2012-06-07 | — | — | US | disclosed |
| US-20110040125-A1 | NITROGEN AND HINDERED PHENOL CONTAINING DUAL FUNCTIONAL MACROMOLECULAR ANTIOXIDANTS: SYNTHESIS, PERFORMANCES AND APPLICATIONS | POLNOX CORPORATION (US) | 2011-02-17 | — | — | US | disclosed |
| US-7799948-B2 | stabilizers for inhibiting oxidation in organic materials, lubricants and petroleum based products, plastics and elastomers, cosmetics, foods and cooking oils | POLNOX CORPORATION (US) | 2010-09-21 | — | — | US | disclosed |
| US-7705075-B2 | Stabilized polyolefin compositions | POLNOX CORPORATION (US) | 2010-04-27 | — | — | US | disclosed |
| US-20080293856-A1 | Stabilized polyolefin compositions | POLNOX CORPORATION | 2008-11-27 | — | — | US | disclosed |
| US-20070161522-A1 | Lubricant oil compositions | POLNOX CORPORATION | 2007-07-12 | — | — | US | disclosed |
| US-20070149660-A1 | Stabilized polyolefin compositions | POLNOX CORPORATION | 2007-06-28 | — | — | US | disclosed |
| US-20070149660-A1 | Stabilized polyolefin compositions | POLNOX CORPORATION | 2007-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140316163-A1 | NITROGEN AND HINDERED PHENOL CONTAINING DUAL FUNCTIONAL MACROMOLECULAR ANTIOXIDANTS: SYNTHESIS, PERFORMANCES AND APPLICATIONS | CAT, LPO, DUOX1 | ALDH1A1 941/4885GAA 1057/4885TSHR 4655/4885 |
| US-20120142968-A1 | Nitrogen and Hindered Phenol Containing Dual Functional Macromolecular Antioxidants: Synthesis, Performances and Applications | CAT, LPO, DUOX1 | ALDH1A1 941/4885GAA 1057/4885TSHR 4655/4885 |
| US-20110040125-A1 | NITROGEN AND HINDERED PHENOL CONTAINING DUAL FUNCTIONAL MACROMOLECULAR ANTIOXIDANTS: SYNTHESIS, PERFORMANCES AND APPLICATIONS | CAT, DUOX1, LPO | ALDH1A1 944/4885GAA 1108/4885TSHR 4678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.