Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | RORA | P35398 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10089353 | 0.89 | CYP2D6 (0.34) | CYP2D6CYP2C19CYP1A2CYP2C9HIF1A | |
| SCHEMBL10089389 | 0.84 | CYP2D6 (0.35) | HTR1DCYP2D6CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL10089386 | 0.84 | LMNA (0.33) | CYP2D6CYP2C19CYP1A2CYP2C9HIF1A | |
| SCHEMBL20921602 | 0.84 | HTR1D (0.39) | HTR1DCYP2D6CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL15912544 | 0.83 | CYP2C19 (0.34) | CYP2D6CYP2C19CYP1A2CYP2C9HIF1A | |
| SCHEMBL20614606 | 0.83 | HTR1D (0.38) | HTR1DCYP2D6CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL14773892 | 0.82 | FOLH1 (0.35) | CYP2D6CYP2C19CYP1A2CYP2C9HIF1A | |
| SCHEMBL20616719 | 0.81 | CYP2D6 (0.39) | HTR1DCYP2D6CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL20616720 | 0.80 | CYP2D6 (0.40) | HTR1DCYP2D6CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL10089385 | 0.75 | CYP2D6 (0.33) | CYP2D6CYP2C19CYP1A2CYP2C9HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383753-B2 | Polydentate heteroatom ligand containing metal complexes, catalysts and methods of making and using the same | DOW GLOBAL TECHNOLOGIES, LLC (US) | 2013-02-26 | — | — | US | disclosed |
| US-8383753-B2 | Polydentate heteroatom ligand containing metal complexes, catalysts and methods of making and using the same | DOW GLOBAL TECHNOLOGIES, LLC (US) | 2013-02-26 | — | — | US | disclosed |
| US-20120029159-A1 | POLYDENTATE HETEROATOM LIGAND CONTAINING METAL COMPLEXES, CATALYSTS AND METHODS OF MAKING AND USING THE SAME | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-02-02 | — | — | US | disclosed |
| US-20120029159-A1 | POLYDENTATE HETEROATOM LIGAND CONTAINING METAL COMPLEXES, CATALYSTS AND METHODS OF MAKING AND USING THE SAME | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-02-02 | — | — | US | disclosed |
| US-8071701-B2 | Polydentate heteroatom ligand containing metal complexes, catalysts and methods of making and using the same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-12-06 | — | — | US | disclosed |
| US-8071701-B2 | Polydentate heteroatom ligand containing metal complexes, catalysts and methods of making and using the same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-12-06 | — | — | US | disclosed |
| US-20090221770-A1 | POLYDENTATE HETEROATOM LIGAND CONTAINING METAL COMPLEXES, CATALYSTS AND METHODS OF MAKING AND USING THE SAME | DOW GLOBAL TECHNOLOGIES INC. | 2009-09-03 | — | — | US | disclosed |
| US-20090221770-A1 | POLYDENTATE HETEROATOM LIGAND CONTAINING METAL COMPLEXES, CATALYSTS AND METHODS OF MAKING AND USING THE SAME | DOW GLOBAL TECHNOLOGIES INC. | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221770-A1 | POLYDENTATE HETEROATOM LIGAND CONTAINING METAL COMPLEXES, CATALYSTS AND METHODS OF MAKING AND USING THE SAME | PICALM, PARG, POLM | HTR1D 4697/4885CYP2D6 2941/4885CYP2C19 4184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.