Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | CNR2 | P34972 | 1/20 | 0.56 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.55 |
| ▸ | FABP4 | P15090 | 2/20 | 0.51 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 7/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 7/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.50 |
| ▸ | MAOA | P21397 | 5/20 | 0.50 |
| ▸ | MAOB | P27338 | 5/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.49 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29941758 | 1.00 | ALDH1A1 (0.64) | ALDH1A1CNR2PTGER4FABP4FABP5 | |
| SCHEMBL1149879 | 0.88 | PTGER4 (0.67) | ALDH1A1CNR2PTGER4FABP4FABP5 | |
| SCHEMBL27772057 | 0.86 | SMPD1 (0.52) | ALDH1A1CNR2PTGER4MEN1KMT2A | |
| SCHEMBL3943747 | 0.84 | CNR2 (0.51) | ALDH1A1CNR2PTGER4FABP4FABP5 | |
| SCHEMBL30294930 | 0.81 | MEN1 (0.70) | ALDH1A1PTGER4FABP4FABP5MEN1 | |
| SCHEMBL30716978 | 0.81 | MEN1 (0.70) | ALDH1A1PTGER4FABP4FABP5MEN1 | |
| SCHEMBL13387568 | 0.81 | MEN1 (0.70) | ALDH1A1PTGER4FABP4FABP5MEN1 | |
| SCHEMBL14578721 | 0.81 | MEN1 (0.70) | ALDH1A1PTGER4FABP4FABP5MEN1 | |
| SCHEMBL4552166 | 0.81 | FABP4 (0.64) | ALDH1A1FABP4FABP5MEN1KMT2A | |
| SCHEMBL4552481 | 0.81 | FABP4 (0.68) | FABP4FABP5GRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855458-B1 | CARBAZOLE-CONTAINING SULFONAMIDES AS CRYPTOCHROME MODULATORS | RESET THERAPEUTICS INC (US) | 2018-08-08 | — | — | EP | disclosed |
| US-8148541-B2 | Rhodanine derivatives, a process for the preparation thereof and pharmaceutical composition containing the same | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2012-04-03 | — | — | US | disclosed |
| US-20090042872-A1 | Rhodanine Derivatives, a Process for the Preparation Thereof and Pharmaceutical Composition Containing the Same | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042872-A1 | Rhodanine Derivatives, a Process for the Preparation Thereof and Pharmaceutical Composition Containing the Same | PTPRR, PTPRG, PTPRS | ALDH1A1 2660/4885CNR2 3622/4885PTGER4 4829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.