Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTP4A3 | O75365 | 3/20 | 0.68 |
| ▸ | CRHBP | P24387 | 2/20 | 0.68 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.68 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.58 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.58 |
| ▸ | NAT1 | P18440 | 4/20 | 0.56 |
| ▸ | MYC | P01106 | 1/20 | 0.56 |
| ▸ | MAX | P61244 | 1/20 | 0.56 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.53 |
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | MGAM | O43451 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SI | P14410 | 1/20 | 0.51 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.51 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14610176 | 0.89 | PTP4A3 (0.70) | PTP4A3CRHBPCRHR2PLA2G1BATG4B | |
| SCHEMBL2065487 | 0.88 | CRHBP (0.72) | PTP4A3CRHBPCRHR2PLA2G1BATG4B | |
| SCHEMBL2065485 | 0.88 | CRHBP (0.72) | PTP4A3CRHBPCRHR2PLA2G1BATG4B | |
| SCHEMBL18102858 | 0.82 | PTP4A3 (0.75) | PTP4A3CRHBPCRHR2PLA2G1BATG4B | |
| SCHEMBL28965550 | 0.81 | PTP4A3 (1.00) | PTP4A3CRHBPCRHR2PLA2G1BATG4B | |
| SCHEMBL13499573 | 0.80 | CRHBP (0.68) | PTP4A3CRHBPCRHR2PLA2G1BATG4B | |
| SCHEMBL14899471 | 0.79 | PTP4A3 (0.75) | PTP4A3CRHBPCRHR2PLA2G1BATG4B | |
| SCHEMBL18102957 | 0.79 | PTP4A3 (0.71) | PTP4A3CRHBPCRHR2PLA2G1BATG4B | |
| SCHEMBL12204299 | 0.79 | PTP4A3 (0.79) | PTP4A3CRHBPCRHR2PLA2G1BATG4B | |
| SCHEMBL20535130 | 0.79 | PTP4A3 (0.79) | PTP4A3CRHBPCRHR2PLA2G1BATG4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148541-B2 | Rhodanine derivatives, a process for the preparation thereof and pharmaceutical composition containing the same | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2012-04-03 | — | — | US | disclosed |
| US-20090042872-A1 | Rhodanine Derivatives, a Process for the Preparation Thereof and Pharmaceutical Composition Containing the Same | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042872-A1 | Rhodanine Derivatives, a Process for the Preparation Thereof and Pharmaceutical Composition Containing the Same | PTPRR, PTPRG, PTPRS | PTP4A3 28/4885CRHBP 480/4885CRHR2 1251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.