Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 3/20 | 0.68 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.68 |
| ▸ | PTP4A3 | O75365 | 2/20 | 0.68 |
| ▸ | GSK3B | P49841 | 2/20 | 0.57 |
| ▸ | PIM1 | P11309 | 1/20 | 0.56 |
| ▸ | NAT1 | P18440 | 4/20 | 0.56 |
| ▸ | MYC | P01106 | 1/20 | 0.56 |
| ▸ | MAX | P61244 | 1/20 | 0.56 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.53 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.52 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 2/20 | 0.51 |
| ▸ | CASP9 | P55211 | 2/20 | 0.51 |
| ▸ | CASP6 | P55212 | 2/20 | 0.51 |
| ▸ | TDP2 | O95551 | 1/20 | 0.51 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.51 |
| ▸ | IGF1R | P08069 | 1/20 | 0.50 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2065487 | 0.90 | CRHBP (0.72) | CRHBPCRHR2PTP4A3GSK3BPIM1 | |
| SCHEMBL2065485 | 0.90 | CRHBP (0.72) | CRHBPCRHR2PTP4A3GSK3BPIM1 | |
| SCHEMBL10438698 | 0.86 | CRHBP (0.64) | CRHBPCRHR2PTP4A3GSK3BPIM1 | |
| SCHEMBL8310830 | 0.82 | TDP2 (0.75) | CRHBPCRHR2PTP4A3GSK3BPIM1 | |
| SCHEMBL8310829 | 0.82 | TDP2 (0.75) | CRHBPCRHR2PTP4A3GSK3BPIM1 | |
| SCHEMBL20535130 | 0.81 | PTP4A3 (0.79) | CRHBPCRHR2PTP4A3PIM1NAT1 | |
| SCHEMBL20535128 | 0.81 | PTP4A3 (0.79) | CRHBPCRHR2PTP4A3PIM1NAT1 | |
| SCHEMBL12204299 | 0.81 | PTP4A3 (0.79) | CRHBPCRHR2PTP4A3PIM1NAT1 | |
| SCHEMBL28965550 | 0.81 | PTP4A3 (1.00) | CRHBPCRHR2PTP4A3PIM1NAT1 | |
| SCHEMBL14610176 | 0.81 | PTP4A3 (0.70) | CRHBPCRHR2PTP4A3PIM1NAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431376-B2 | Bacterial replication systems and methods | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2013-04-30 | — | — | US | disclosed |
| US-8431376-B2 | Bacterial replication systems and methods | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2013-04-30 | — | — | US | disclosed |
| US-20100028862-A1 | BACTERIAL REPLICATION SYSTEMS AND METHODS | Replidyne,Inc. (US) | 2010-02-04 | — | — | US | disclosed |
| WO-2006071255-A9 | BACTERIAL REPLICATION SYSTEMS AND METHODS | REPLIDYNE INC (US) | 2007-02-15 | — | — | WO | disclosed |