SCHEMBL10090536

SCHEMBL10090536

CC(C)(C)Cc1ccc2c3ccc(CC(C)(C)C)cc3n(-c3cccc(-c4cccc(-n5c6ccccc6c6ccccc65)c4)c3)c2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
ATM Q13315 1/20 0.41
HPGD P15428 3/20 0.35
ALDH1A1 P00352 3/20 0.35
HSD17B10 Q99714 1/20 0.35
RXRA P19793 1/20 0.35
RXRB P28702 1/20 0.35
KMT2A Q03164 2/20 0.33
MAPT P10636 2/20 0.33
TSHR P16473 1/20 0.33
IL1R1 P14778 1/20 0.33
CYP1A2 P05177 1/20 0.33
GLA P06280 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
MEN1 O00255 1/20 0.33
HTT P42858 1/20 0.33
F2 P00734 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10090525 1.00 KDM4E (0.41) KDM4EL3MBTL1ATMHPGDALDH1A1
SCHEMBL8739893 0.92 KDM4E (0.41) KDM4EL3MBTL1ATMHPGDALDH1A1
SCHEMBL8739896 0.92 KDM4E (0.41) KDM4EL3MBTL1ATMHPGDALDH1A1
SCHEMBL22986683 0.89 KDM4E (0.55) KDM4EL3MBTL1ATMHPGDALDH1A1
SCHEMBL22177160 0.89 KDM4E (0.48) KDM4EL3MBTL1ATMHPGDALDH1A1
SCHEMBL10090549 0.85 ICMT (0.36) KDM4EL3MBTL1ATMHPGDALDH1A1
SCHEMBL13174410 0.85 KDM4E (0.39) KDM4EL3MBTL1ATMHPGDALDH1A1
SCHEMBL12832240 0.84
SCHEMBL8739909 0.83 KDM4E (0.43) KDM4EL3MBTL1ATMHPGDALDH1A1
SCHEMBL10090547 0.82 RORC (0.36) KDM4EL3MBTL1ATMMAPTPLA2G10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120161617-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-06-28 US disclosed
US-20120161617-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-06-28 US disclosed