SCHEMBL10092

SCHEMBL10092

Nc1ccc(OCC(F)(F)F)nc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.56
KDM4E B2RXH2 5/20 0.47
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
POLB P06746 2/20 0.47
MAPK1 P28482 1/20 0.47
MAPT P10636 4/20 0.46
ALDH1A1 P00352 4/20 0.46
RAB9A P51151 1/20 0.44
CYP1A2 P05177 1/20 0.43
KEAP1 Q14145 1/20 0.42
HSD17B10 Q99714 2/20 0.41
USP2 O75604 1/20 0.41
HSP90AA1 P07900 1/20 0.41
HSP90AB1 P08238 1/20 0.41
THRB P10828 1/20 0.41
G6PD P11413 1/20 0.41
ALOX15 P16050 1/20 0.41
CASP1 P29466 1/20 0.41
EPHX2 P34913 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29516441 1.00 L3MBTL1 (0.56) L3MBTL1KDM4EMEN1KMT2APOLB
Hydrochloric Acid SCHEMBL1496776 0.98 L3MBTL1 (0.54) L3MBTL1KDM4EMEN1KMT2APOLB
SCHEMBL3884547 0.82 KDM4E (0.42) L3MBTL1KDM4EMEN1KMT2APOLB
SCHEMBL744042 0.81 EPHX2 (0.46) L3MBTL1KDM4EMEN1KMT2APOLB
Hydrochloric Acid SCHEMBL1496814 0.79 KDM4E (0.50) L3MBTL1KDM4EMEN1KMT2APOLB
SCHEMBL2145798 0.79 L3MBTL1 (0.50) L3MBTL1POLBMAPK1MAPTCYP1A2
SCHEMBL3890599 0.78 L3MBTL1 (0.53) L3MBTL1POLBMAPK1MAPTALDH1A1
SCHEMBL30939139 0.78 L3MBTL1 (0.53) L3MBTL1POLBMAPK1MAPTALDH1A1
SCHEMBL2228010 0.78 KDM4E (0.49) L3MBTL1KDM4EMEN1KMT2APOLB
SCHEMBL20886038 0.78 KDM4E (0.52) L3MBTL1KDM4EMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113737183-B Selective copper etching solution 湖北兴福电子材料有限公司 2022-08-05 CN claimed
CN-114350365-A Etching solution for stably etching titanium nitride 湖北兴福电子材料有限公司 2022-04-15 CN claimed
CN-113737183-A Selective copper etching solution 湖北兴福电子材料有限公司 2021-12-03 CN claimed
EP-4702021-A1 COMPOUNDS CAPABLE OF MODULATING GPR65 Pathios Therapeutics Limited (GB) 2026-03-04 EP disclosed
WO-2024224064-A1 COMPOUNDS CAPABLE OF MODULATING GPR65 Pathios Therapeutics Limited (GB) 2024-10-31 WO disclosed
US-20240173307-A1 MODULATORS OF THE INTEGRATED STRESS PATHWAY ABBVIE INC. 2024-05-30 US disclosed
US-11939320-B2 Modulators of the integrated stress pathway ABBVIE INC. (US) 2024-03-26 US disclosed
CN-112204006-B Modulators of integrated stress pathways 卡里科生命科学有限责任公司 2023-11-28 CN disclosed
EP-3704089-B1 MODULATORS OF THE INTEGRATED STRESS PATHWAY CALICO LIFE SCIENCES LLC (US) 2023-07-19 EP disclosed
CN-113754679-B Substituted pyrimidinediones and their use 广东东阳光药业有限公司 2023-04-07 CN disclosed
WO-2022266458-A1 6-HETEROCYCLOALKYL-QUINAZOLINE DERIVATIVES AND USES THEREOF BLACK DIAMOND THERAPEUTICS, INC. (US) 2022-12-22 WO disclosed
EP-0454831-B1 Diazine derivatives as angiotensin II receptor antagonists ICI PLC (GB) 1994-08-03 EP disclosed
US-5126344-A Angiotensin antagonists IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-06-30 US disclosed
EP-0454831-A1 Diazine derivatives as angiotensin II receptor antagonists. ICI PLC (GB) 1991-11-06 EP disclosed
WO-1991007404-A1 DIAZINE DERIVATIVES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-05-30 WO disclosed
US-4897415-A NEMATOCIDES SCHERING AKTIENGESELLSCHAFT (DE) 1990-01-30 US disclosed
CN-88100536-A 2-imino--1,3-dithio-cyclobutane compounds and preparation method thereof and as the application of sterilant 1988-09-14 CN disclosed
EP-0277091-A2 2-Imino-1,3-dithietanes, their preparation and use as pesticides SCHERING AKTIENGESELLSCHAFT (DE) 1988-08-03 EP disclosed
EP-0008881-A1 1-Benzoyl-3-pyridinyl ureas, their use as insecticides, their preparation and formulations containing them ELI LILLY AND COMPANY (US) 1980-03-19 EP disclosed
US-4173639-A INSECTICIDES ELI LILLY AND COMPANY (US) 1979-11-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240173307-A1 MODULATORS OF THE INTEGRATED STRESS PATHWAY ATF4, ATF1, DDIT3 L3MBTL1 1651/4885KDM4E 4646/4885MEN1 4714/4885
US-11939320-B2 Modulators of the integrated stress pathway ATF4, ATF1, DDIT3 L3MBTL1 1651/4885KDM4E 4646/4885MEN1 4714/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.