SCHEMBL10092104

SCHEMBL10092104

C=C1CSCC(OC(=O)c2ccccc2)SC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 2/20 0.38
TRPM8 Q7Z2W7 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
GAA P10253 1/20 0.38
LMNA P02545 2/20 0.37
F2 P00734 1/20 0.37
HTR3E A5X5Y0 1/20 0.37
HTR3B O95264 1/20 0.37
HTR3A P46098 1/20 0.37
HTR3D Q70Z44 1/20 0.37
HTR3C Q8WXA8 1/20 0.37
ALDH1A1 P00352 2/20 0.36
PKM P14618 1/20 0.36
APOBEC3A P31941 1/20 0.36
APOBEC3G Q9HC16 1/20 0.36
TSHR P16473 2/20 0.35
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35
CHRM1 P11229 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10092005 0.84 CHRNA7 (0.48) CHRNA7TRPM8MEN1KMT2AGAA
SCHEMBL10092009 0.75 PTPN1 (0.54) CHRNA7LMNAALDH1A1TSHRPTPN2
SCHEMBL14432297 0.75
SCHEMBL10092015 0.70 CHRNA7 (0.41) CHRNA7TRPM8MEN1KMT2AGAA
SCHEMBL10092004 0.70 PTPN1 (0.68) MEN1KMT2AALDH1A1TSHRPTPN2
SCHEMBL10092182 0.70 PTPN1 (0.48) CHRNA7LMNAALDH1A1TSHRPTPN2
SCHEMBL11047049 0.68 KMT2A (0.49) CHRNA7MEN1KMT2AGAALMNA
SCHEMBL11044178 0.67 KMT2A (0.48) CHRNA7MEN1KMT2AGAALMNA
SCHEMBL14039909 0.67 PTPN1 (0.53) MEN1KMT2ALMNAALDH1A1TSHR
SCHEMBL22692817 0.66 BCHE (0.51) CHRNA7MEN1KMT2AGAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120019938-A1 CURABLE RESIN COMPOSITION FOR CEMENTED LENS, IMAGING LENS, AND METHOD FOR MANUFACTURING IMAGING LENS FUJIFILM CORPORATION (JP) 2012-01-26 US disclosed
US-20120019938-A1 CURABLE RESIN COMPOSITION FOR CEMENTED LENS, IMAGING LENS, AND METHOD FOR MANUFACTURING IMAGING LENS FUJIFILM CORPORATION (JP) 2012-01-26 US disclosed
US-20100241225-A1 CURABLE RESIN COMPOSITION FOR INTRAOCULAR LENS, INTRACULAR LENS MATERIAL AND INTRACULAR LENS FUJIFILM CORPORATION (JP) 2010-09-23 US disclosed
US-20100241225-A1 CURABLE RESIN COMPOSITION FOR INTRAOCULAR LENS, INTRACULAR LENS MATERIAL AND INTRACULAR LENS FUJIFILM CORPORATION (JP) 2010-09-23 US disclosed
US-20090142671-A1 OPTICAL RECORDING COMPOSITION AND HOLOGRAPHIC RECORDING MEDIUM FUJIFILM CORPORATION (JP) 2009-06-04 US disclosed
US-20090142671-A1 OPTICAL RECORDING COMPOSITION AND HOLOGRAPHIC RECORDING MEDIUM FUJIFILM CORPORATION (JP) 2009-06-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090142671-A1 OPTICAL RECORDING COMPOSITION AND HOLOGRAPHIC RECORDING MEDIUM CACNA1S, CACNA1E, CRY1 CHRNA7 406/4885TRPM8 720/4885MEN1 1298/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.