SCHEMBL10092199

SCHEMBL10092199

c1ccc2c(c1)oc1c(-n3c4ccccc4c4cc(-c5cccc6c5oc5ccc(-n7c8ccccc8c8ccccc87)cc56)ccc43)cccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.47
PRKDC P78527 5/20 0.41
GGPS1 O95749 1/20 0.39
PTGES2 Q9H7Z7 1/20 0.35
PRMT5 O14744 1/20 0.35
WDR77 Q9BQA1 1/20 0.35
EDNRB P24530 1/20 0.33
EDNRA P25101 1/20 0.33
ATM Q13315 2/20 0.33
PIK3CD O00329 1/20 0.31
PIK3CB P42338 1/20 0.31
HSP90AA1 P07900 1/20 0.31
HSP90AB1 P08238 1/20 0.31
KDM4E B2RXH2 2/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MEN1 O00255 1/20 0.30
NPC1 O15118 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5029690 1.00 ALOX5 (0.47) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL14849210 1.00 ALOX5 (0.47) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL5028288 1.00 ALOX5 (0.47) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL5028173 0.98 ALOX5 (0.43) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL10092187 0.98 ALOX5 (0.43) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL12925677 0.94 ALOX5 (0.40) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL5030361 0.94 ALOX5 (0.46) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL17248353 0.93 ALOX5 (0.51) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL20715118 0.93 ALOX5 (0.51) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL20654715 0.93 ALOX5 (0.42) ALOX5PRKDCGGPS1PTGES2PRMT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2453496-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, NOVEL COMPOUND, LIGHTING DEVICE AND DISPLAY DEVICE Konica Minolta Holdings, Inc. (JP) 2012-05-16 EP disclosed
US-20110006670-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, NEW COMPOUND FOR THE SAME, DISPLAY DEVICE AND LIGHTING DEVICE USING THE SAME KONICA MINOLTA HOLDINGS, INC. (JP) 2011-01-13 US disclosed
US-20110006670-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, NEW COMPOUND FOR THE SAME, DISPLAY DEVICE AND LIGHTING DEVICE USING THE SAME KONICA MINOLTA HOLDINGS, INC. (JP) 2011-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110006670-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, NEW COMPOUND FOR THE SAME, DISPLAY DEVICE AND LIGHTING DEVICE USING THE SAME AOC2, AOC3, CDYL ALOX5 855/4885PRKDC 3081/4885GGPS1 2906/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.