Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | NMT1 | P30419 | 3/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MPI | P34949 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | GALK1 | P51570 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14981439 | 0.84 | PDE5A (0.38) | GAASMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL13233140 | 0.81 | GAA (0.59) | GAASMN1; SMN2LMNAKDM4EHTT | |
| SCHEMBL11341083 | 0.78 | SMN1; SMN2 (0.35) | GAASMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL14923165 | 0.78 | GAA (0.42) | GAASMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL23400716 | 0.78 | SMN1; SMN2 (0.38) | GAASMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL24786861 | 0.77 | HTR7 (0.41) | GAANMT1 | |
| SCHEMBL24786522 | 0.77 | GAA (0.33) | GAAKDM4E | |
| SCHEMBL26945695 | 0.74 | GAA (0.38) | GAAALDH1A1KDM4E | |
| SCHEMBL23587194 | 0.74 | GAA (0.42) | GAASMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL19399308 | 0.74 | NMT1 (0.36) | GAAALDH1A1NMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012024670-A2 | COMPOSITION AND METHODS FOR TREATING GLIOBLASTOMA | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2012-02-23 | — | — | WO | disclosed |